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血糖变异性对外科手术患者的影响。

The impact of glycaemic variability on the surgical patient.

作者信息

Dhatariya Ketan, Levy Nicholas, Hall George M

机构信息

aElsie Bertram Diabetes Centre, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, Norfolk bDepartment of Anaesthesia, West Suffolk NHS Foundation Trust, Hardwick Lane, Bury St Edmunds, Suffolk cDepartment of Anaesthesia and Intensive Care Medicine, St. George's Hospital Medical School, London, UK.

出版信息

Curr Opin Anaesthesiol. 2016 Jun;29(3):430-7. doi: 10.1097/ACO.0000000000000326.

Abstract

PURPOSE OF REVIEW

Diabetes is the most prevalent long-term metabolic condition and its incidence continues to increase unabated. Patients with diabetes are overrepresented in the surgical population. It has been well recognized that poor perioperative diabetes control is associated with poor surgical outcomes. The outcomes are worst for those people who were not recognized as having hyperglycaemia.

RECENT FINDINGS

Recent work has shown that preoperative recognition of diabetes and good communication between the clinical teams at all stages of the patient pathway help to minimize the potential for errors, and improve glycaemic control. The stages of the patient journey start in primary care and end when the patient goes home. The early involvement of the diabetes specialist team is important if the glycated haemoglobin is more than 8.5%, and advice sought if the preoperative assessment team is not familiar with the drug regimens. To date the glycaemic targets for the perioperative period have remained uncertain, but recently a consensus is being reached to ensure glucose levels remain between 108 and180 mg/dl (6.0 and 10.0 mmol/l). There have been a number of ways to achieve these - primarily by manipulating the patients' usual diabetes medications, to also allow day of surgery admission.

SUMMARY

glycaemic control remains an important consideration in the surgical patient.

摘要

综述目的

糖尿病是最常见的长期代谢性疾病,其发病率持续上升且毫无减缓之势。糖尿病患者在外科手术人群中占比过高。人们已经充分认识到围手术期糖尿病控制不佳与手术效果不佳相关。对于那些未被识别为患有高血糖症的人来说,手术结果最差。

最新发现

近期研究表明,术前识别糖尿病以及患者就医全过程中临床团队各阶段的良好沟通有助于将潜在错误降至最低,并改善血糖控制。患者就医过程始于初级保健,止于患者回家。如果糖化血红蛋白超过8.5%,糖尿病专科团队的早期介入很重要;如果术前评估团队不熟悉药物治疗方案,则应寻求相关建议。迄今为止,围手术期的血糖目标仍不明确,但最近正在达成共识,以确保血糖水平维持在108至180毫克/分升(6.0至10.0毫摩尔/升)之间。实现这些目标有多种方法——主要是通过调整患者常用的糖尿病药物,同时也允许患者在手术当天入院。

总结

血糖控制仍然是外科手术患者的一个重要考量因素。

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