Meyer J M, Fabre M, Staubli A, Ruch J V
J Biol Buccale. 1977 Jun;5(2):107-19.
Epithelial-mesenchyme interactions during mouse molar tooth morphogenesis were observed by electron microscopy. The basal lamina was intact from day 10 to day 18. Aperiodic, later also periodic fibrils were deposited on the basal lamina. Ectomesenchymal cell processes were always in close relation with the basal lamina or with the fibrillar material. On day 19 some direct heterotypic cell contacts between odontoblasts and preameloblasts were observed. At all stages, especially the preodontoblasts but also preameloblasts, gave rise to aggregated vesicles, which were extruded in the epithelial-mesenchymal space.
通过电子显微镜观察了小鼠磨牙牙形态发生过程中的上皮-间充质相互作用。从第10天到第18天,基膜完整。无定形的、后来也有周期性的纤维沉积在基膜上。外间充质细胞突起总是与基膜或纤维状物质密切相关。在第19天,观察到成牙本质细胞和成釉细胞之间有一些直接的异型细胞接触。在所有阶段,尤其是前成牙本质细胞,但也包括前成釉细胞,会产生聚集的小泡,这些小泡被挤压到上皮-间充质空间中。