他汀类药物的使用对经椎间孔硬膜外类固醇注射缓解疼痛的影响。
Effect of statin use on pain relief by transforaminal epidural steroid injection.
作者信息
Sari Sinem, Aydın Osman Nuri, Tasdemir Banu, Galimberti Fabrizio, Turan Alparslan
机构信息
Department of Anaesthesia and Reanimation, Adnan Menderes University Medical Faculty, Aydin, Turkey
Department of Algology, Adnan Menderes University, Aydin, Turkey.
出版信息
J Int Med Res. 2016 Apr;44(2):389-94. doi: 10.1177/0300060515597934. Epub 2016 Feb 19.
AIM
To investigate the impact of statin use on response to fluoroscopy-assisted transforaminal anterior epidural steroid injection (TAESI).
METHODS
Patients undergoing TAESI for low back pain were recruited and stratified according to statin use. Pain was evaluated with a visual analogue scale (VAS) before and at 1, 3, and 6 months after TAESI. Health-related quality-of-life was evaluated using the Short Form 36 (SF-36) questionnaire 6 months after TAESI.
RESULTS
There were no significant differences in VAS scores after TAESI between statin users (n = 40) and statin nonusers (n = 253). The SF-36 subgroup: role limitations due to emotional problems score was significantly lower in statin users than statin nonusers. There were no significant between-group differences in any other SF-36 parameter.
CONCLUSION
Statin use had no effect on pain scores after TAESI.
目的
探讨使用他汀类药物对透视辅助下经椎间孔前路硬膜外类固醇注射（TAESI）疗效的影响。
方法
招募因腰痛接受TAESI治疗的患者，并根据他汀类药物使用情况进行分层。在TAESI治疗前以及治疗后1、3和6个月，使用视觉模拟量表（VAS）评估疼痛程度。在TAESI治疗6个月后，使用简明健康状况调查量表（SF-36）问卷评估健康相关生活质量。
结果
使用他汀类药物的患者（n = 40）和未使用他汀类药物的患者（n = 253）在TAESI治疗后的VAS评分无显著差异。SF-36亚组中，使用他汀类药物的患者因情感问题导致的角色限制评分显著低于未使用他汀类药物的患者。在其他任何SF-36参数方面，组间均无显著差异。
结论
使用他汀类药物对TAESI治疗后的疼痛评分无影响。
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