Wang He, Fan Yan-Yan, Kudinha Timothy, Xu Zhi-Peng, Xiao Meng, Zhang Li, Fan Xin, Kong Fanrong, Xu Ying-Chun
Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
J Clin Microbiol. 2016 May;54(5):1376-80. doi: 10.1128/JCM.00162-16. Epub 2016 Feb 24.
Among the 2,683 yeast isolates representing 41 different species (25 Candida and Candida-related species and 16 non-Candida yeast species) collected in the National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) program (2012 to 2013), the Bruker Biotyper MS matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) system exhibited significantly higher accuracy rates than the Vitek MS system for identification of all yeast isolates (98.8% versus 95.4%, P <0.001 by Pearson's chi-square test) and for all Candida and Candida-related species isolates (99.4% versus 95.5%, P < 0.001).
在中国全国医院侵袭性真菌监测网(CHIF-NET)项目(2012年至2013年)收集的代表41种不同酵母菌种(25种念珠菌及念珠菌相关菌种和16种非念珠菌酵母菌种)的2683株酵母分离株中,布鲁克微生物鉴定仪基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)系统在鉴定所有酵母分离株(98.8%对95.4%,Pearson卡方检验P<0.001)以及所有念珠菌和念珠菌相关菌种分离株(99.4%对95.5%,P<0.001)方面,准确率显著高于Vitek MS系统。