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18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG PET/CT)上骨髓摄取不均一并不总是淋巴瘤累及的征象。

Heterogeneous Marrow Uptake on FDG PET/CT is not Always a Sign of Lymphomatous Involvement.

作者信息

Reddy Gorla Arun Kumar, Mittal Bhagwant Rai, Bhattacharya Anish, Malhotra Pankaj, Varma Subhash

机构信息

Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, Haryana and Punjab, India.

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, Haryana and Punjab, India.

出版信息

World J Nucl Med. 2016 Jan-Apr;15(1):59-61. doi: 10.4103/1450-1147.167596.

DOI:10.4103/1450-1147.167596
PMID:26912982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4729018/
Abstract

Heterogeneous patchy marrow uptake on fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in a histologically proven case of lymphoma is usually considered a virtually pathognomonic sign of lymphomatous involvement. Here, we present a young male patient of T-cell-rich non-Hodgkin lymphoma (NHL), an uncommon morphologic variant of diffuse large B-cell lymphoma (DLBCL), who had undergone three sequential PET/CT scans at our department during the course of his therapy. These images depict the need for careful direct comparison of the current study with the previous PET/CT studies to avoid erroneous interpretation.

摘要

在一例经组织学证实的淋巴瘤患者中,氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG-PET/CT)显示的异质性斑片状骨髓摄取通常被认为是淋巴瘤累及的几乎具有诊断意义的征象。在此,我们报告一名年轻男性患者,患有富含T细胞的非霍奇金淋巴瘤(NHL),这是弥漫性大B细胞淋巴瘤(DLBCL)的一种罕见形态学变异型,在其治疗过程中于我院接受了三次连续的PET/CT扫描。这些图像表明,需要将当前研究与之前的PET/CT研究进行仔细的直接比较,以避免错误解读。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b62/4729018/716c4940e6b7/WJNM-15-59-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b62/4729018/716c4940e6b7/WJNM-15-59-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b62/4729018/716c4940e6b7/WJNM-15-59-g001.jpg

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本文引用的文献

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Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma--endpoints of a spectrum of one disease?结节性淋巴细胞为主型霍奇金淋巴瘤和富于T细胞/组织细胞的大B细胞淋巴瘤——一种疾病谱系的终点?
PLoS One. 2013 Nov 11;8(11):e78812. doi: 10.1371/journal.pone.0078812. eCollection 2013.
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Rev Esp Med Nucl Imagen Mol. 2012 Nov-Dec;31(6):340-9. doi: 10.1016/j.remn.2012.06.001. Epub 2012 Jul 26.
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