Nakhaei Amroodi Morteza, Iri Abdolrazzagh, Akhoondi Salehe
Assistant Professor, Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Orthopedic Resident, Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2015 Nov 21;29:298. eCollection 2015.
Prevalence of recurrent shoulder dislocation in patients taking tramadol has not been studied yet; so, this study aims to study the recurrent shoulder dislocation following tramadol induced seizure.
In this cross-sectional study, 205 patients with recurrent shoulder dislocation complaints (2 or more) referred to Shafa Orthopedic and Iranmehr hospitals Tehran, Iran, from October 2012 to October 2014 were studied. Data on patient history and physical examination, patient demographic information such as age, sex, age at first dislocation, total number of dislocation, cause of the first dislocation, history of tramadol use, number of dislocation following tramadol induced seizure, history of other drugs use, the dominant hand, involved side, direction of dislocations and greater tuberosity fracture was recorded using a pre-designed questionnaire. Categorical variables were compared by chi-square test and the means were compared with student T-test.
In this study, 50 patients (24.4%) suffered from tramadol induced seizures and recurrent shoulder dislocation. RESULTS showed that there was a significant relationship between the number of dislocation and tramadol use (P = 0.02). Recurrent shoulder dislocation following tramadol induced seizure was significantly associated with greater tuberosity fracture of humerus (P = 0.04); in 49 out of 50 patients (98%) dislocation was of anterior type.
The findings of this study suggest that tramadol induced seizure may increase the risk of recurrent shoulder dislocation. Furthermore, the prevalence of greater tuberosity fracture in shoulder dislocation increases following tramadol induced seizure; and anterior shoulder dislocation is the most common type of dislocation following tramadol induced seizure.
服用曲马多患者复发性肩关节脱位的患病率尚未得到研究；因此，本研究旨在探讨曲马多诱发癫痫发作后复发性肩关节脱位的情况。
在这项横断面研究中，对2012年10月至2014年10月转诊至伊朗德黑兰沙法骨科医院和伊朗梅尔医院的205例有复发性肩关节脱位主诉（2次或更多次）的患者进行了研究。使用预先设计的问卷记录患者病史和体格检查、患者人口统计学信息，如年龄、性别、首次脱位年龄、脱位总数、首次脱位原因、曲马多使用史、曲马多诱发癫痫发作后的脱位次数、其他药物使用史、优势手、受累侧、脱位方向和大结节骨折情况。分类变量采用卡方检验进行比较，均值采用学生t检验进行比较。
在本研究中，50例患者（24.4%）出现曲马多诱发的癫痫发作和复发性肩关节脱位。结果显示脱位次数与曲马多使用之间存在显著相关性（P = 0.02）。曲马多诱发癫痫发作后的复发性肩关节脱位与肱骨大结节骨折显著相关（P = 0.04）；50例患者中有49例（98%）脱位为前脱位类型。
本研究结果表明，曲马多诱发的癫痫发作可能会增加复发性肩关节脱位的风险。此外，曲马多诱发癫痫发作后肩关节脱位中大结节骨折的患病率增加；前肩关节脱位是曲马多诱发癫痫发作后最常见的脱位类型。
