碘，一种温和的萜类化合物芳香化试剂。

Iodine, a Mild Reagent for the Aromatization of Terpenoids.

机构信息

Department of Organic Chemistry, Institute of Biotechnology, University of Granada , Avenida Fuentenueva, 18071 Granada, Spain.

FibEnTech-Materiais Fibrosos e Tecnologias Ambientais, Department of Chemistry, University of Beira Interior , Rua Marquês d'Ávila e Bolama, 6200 Covilhã, Portugal.

出版信息

J Nat Prod. 2016 Apr 22;79(4):831-7. doi: 10.1021/acs.jnatprod.5b00914. Epub 2016 Feb 25.

DOI:10.1021/acs.jnatprod.5b00914

PMID:26913544

Abstract

Efficient procedures based on the use of iodine for the aromatization of a series of terpenoids possessing diene and homoallylic or allylic alcohol functionalities are described. Different examples are reported as a proof-of-concept study. Furthermore, iodine also proved to mediate the dehydrogenation of testosterone.

摘要

本文描述了一系列具有二烯、偕二烯或烯丙醇官能团的萜烯类化合物进行芳构化反应的高效碘基方法。不同的例子被报道作为概念验证研究。此外，碘还被证明可以介导睾酮的脱氢反应。