Chaparro Raúl M, Em Vargas Verónica, Zorzo Liliana R, Genero Sebastián, Cayre Antonieta
Residencia en Epidemiología, Ministerio de Salud, Resistencia, Chaco, 3500, Argentina.
Programa Ampliado de Inmunizaciones, Ministerio de Salud, Resistencia, Chaco, 3500, Argentina.
Arch Argent Pediatr. 2016 Feb;114(1):36-43. doi: 10.5546/aap.2016.eng.36. Epub 2015 Dec 21.
In Argentina, every year, 3000 new cases of cervical cancer are diagnosed and more than 2000 deaths occur as a result of this disease. Human papillomavirus (HPV) is the main risk factor for cervical carcinogenesis.
To establish the extent of acceptance of HPV vaccines and associated factors among legal guardians of candidate girls in an area of Resistencia, Chaco.
Qualitative and quantitative study. A single randomized sampling was done based on school enrollment lists. Guardians who reported making decisions regarding girls' health in 2012 were included. A structured questionnaire made up of four constructs was used to measure overall acceptability. The association between overall acceptability and sociodemographic outcome measures was assessed.
The rate of acceptance was 46.6% (95% confidence interval: 34.8-58.6). Among guardians, 84.2% were women; their mean age was 38.3 years old (95% confidence interval: 36.7-39.8). Religion was practiced by 86.8% (77.1-93.5), 55.2% were Catholic and 44.8%, Evangelical Protestants. Guardians with more than one candidate girl for the vaccine accounted for 18.9%. Also, 85.5% referred having heard about the virus at some point, and 52.7% knew that a vaccine could prevent it. Acceptance was significantly higher among guardians of those girls who had received the first vaccine dose (OR: 8.02, 95% confidence interval: 2.29-28.01, p= 0.0011).
The rate of acceptance was low and no association was observed between sociodemographic and psychosocial factors and the decision to have girls vaccinated with the HPV vaccine.
在阿根廷，每年有3000例新的宫颈癌病例被诊断出来，并且有超过2000人死于这种疾病。人乳头瘤病毒（HPV）是宫颈癌发生的主要危险因素。
确定查科省雷西斯滕西亚地区候选女孩的法定监护人对HPV疫苗的接受程度及相关因素。
定性和定量研究。基于学校入学名单进行单次随机抽样。纳入了那些报告在2012年对女孩健康做出决策的监护人。使用由四个结构组成的结构化问卷来衡量总体可接受性。评估总体可接受性与社会人口统计学结果指标之间的关联。
接受率为46.6%（95%置信区间：34.8 - 58.6）。在监护人中，84.2%为女性；她们的平均年龄为38.3岁（95%置信区间：36.7 - 39.8）。86.8%（77.1 - 93.5）的人有宗教信仰，55.2%是天主教徒，44.8%是福音派新教徒。有不止一个候选女孩接种疫苗的监护人占18.9%。此外，85.5%的人表示曾在某个时候听说过这种病毒，52.7%的人知道有一种疫苗可以预防它。在那些女孩已经接种了第一剂疫苗的监护人中，接受率显著更高（比值比：8.02，95%置信区间：2.29 - 28.01，p = 0.0011）。
接受率较低，并且未观察到社会人口统计学和心理社会因素与让女孩接种HPV疫苗的决策之间存在关联。
