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接种过疫苗的女性会参加宫颈癌筛查吗?澳大利亚维多利亚州年轻女性中 HPV 疫苗接种和宫颈癌筛查的基于人群调查。

Will vaccinated women attend cervical screening? A population based survey of human papillomavirus vaccination and cervical screening among young women in Victoria, Australia.

机构信息

Victorian Cytology Service, East Melbourne 8002, Victoria, Australia.

出版信息

Cancer Epidemiol. 2012 Jun;36(3):298-302. doi: 10.1016/j.canep.2011.11.005. Epub 2011 Dec 26.

DOI:10.1016/j.canep.2011.11.005
PMID:22204834
Abstract

OBJECTIVES

To assess human papillomavirus (HPV) vaccination coverage and attitudes to vaccination and Pap screening in young women.

DESIGN

Population-based telephone survey.

SETTING

Victoria, Australia.

PARTICIPANTS

234 women resident in Victoria aged 18-28 years in May 2009.

MAIN OUTCOME MEASURES

Self-reported HPV vaccination uptake, reasons for non-receipt or failure to complete vaccination, knowledge and attitudes about HPV vaccination and Pap screening, and cervical screening intentions.

RESULTS

The response rate for eligible households was 62.4%. Half of the women (56%, n=131) had previously had a Pap test and 74% (age standardised estimate) had received HPV vaccine. Of the vaccinated women, 5% had received one dose only, 18% two doses and 76% had completed the course (1.7% unsure of number of doses). Vaccination uptake was highest in the youngest women (declining from 90% for at least one dose in women aged 18-38.5% in women aged 28; p for trend <0.001). Among women who had heard of the vaccine, 96% knew Pap tests were still needed after it, although 20% thought the vaccine could prevent all cervical cancers and 9% thought the vaccine could treat cervical abnormalities and cancer. Among vaccinated women, 8% of women agreed that having been vaccinated made them less likely to have Pap tests in the future.

CONCLUSIONS

Self-reported coverage in this sample was higher than that recorded on the national vaccination register. Young women report the message that Pap tests are required after vaccination, but there are gaps in their knowledge about the limitations of the vaccine so it remains to be seen if they actually follow through with having Pap tests. Ongoing monitoring of cervical screening rates will be important as this cohort ages.

摘要

目的

评估年轻女性中人类乳头瘤病毒(HPV)疫苗接种率以及对疫苗接种和巴氏筛查的态度。

设计

基于人群的电话调查。

地点

澳大利亚维多利亚州。

参与者

2009 年 5 月居住在维多利亚州的 18-28 岁的 234 名女性。

主要观察指标

自我报告的 HPV 疫苗接种率、未接种或未完成接种的原因、对 HPV 疫苗接种和巴氏筛查的知识和态度,以及宫颈癌筛查意向。

结果

符合条件的家庭的应答率为 62.4%。一半的女性(56%,n=131)之前曾进行过巴氏检查,74%(年龄标准化估计)已接种 HPV 疫苗。已接种疫苗的女性中,5%仅接种了 1 剂,18%接种了 2 剂,76%完成了全程接种(1.7%不确定接种了多少剂)。疫苗接种率在最年轻的女性中最高(18-38.5 岁女性中至少接种 1 剂的比例从 90%降至 38.5%;趋势 p<0.001)。在听说过该疫苗的女性中,96%知道接种后仍需要进行巴氏检查,尽管 20%认为该疫苗可以预防所有宫颈癌,9%认为该疫苗可以治疗宫颈癌前病变和癌症。在已接种疫苗的女性中,8%的女性认为接种疫苗后,她们将来不太可能进行巴氏检查。

结论

在该样本中,自我报告的接种率高于全国疫苗接种登记处记录的接种率。年轻女性报告称,接种疫苗后需要进行巴氏检查,但她们对疫苗的局限性的了解存在差距,因此尚不清楚她们是否真的会继续进行巴氏检查。随着这一年龄段女性的年龄增长,对宫颈癌筛查率的持续监测将非常重要。

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