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阿莫西林/克拉维酸与头孢西丁在血管外科手术中的预防作用——一项随机临床研究。

The prophylactic activity of amoxycillin/clavulanate and cefoxitin in vascular surgery--a randomized clinical study.

作者信息

Dieterich H J, Groh J, Behringer K, Lauterjung L, Martin E

机构信息

Institute of Anaesthesiology, Ludwig-Maximilians-University, Klinikum Grosshadern, Munich, FRG.

出版信息

J Antimicrob Chemother. 1989 Nov;24 Suppl B:209-11. doi: 10.1093/jac/24.suppl_b.209.

DOI:10.1093/jac/24.suppl_b.209
PMID:2691482
Abstract

In a randomized clinical study, 141 patients who had to undergo operations on the aorta or the main arteries received either amoxycillin/clavulanate or cefoxitin perioperatively for prophylaxis. As no wound infection occurred amoxycillin/clavulanate and cefoxitin were found to be equal in effectiveness.

摘要

在一项随机临床研究中,141名必须接受主动脉或主要动脉手术的患者在围手术期接受阿莫西林/克拉维酸盐或头孢西丁进行预防。由于未发生伤口感染,发现阿莫西林/克拉维酸盐和头孢西丁的有效性相当。

相似文献

1
The prophylactic activity of amoxycillin/clavulanate and cefoxitin in vascular surgery--a randomized clinical study.阿莫西林/克拉维酸与头孢西丁在血管外科手术中的预防作用——一项随机临床研究。
J Antimicrob Chemother. 1989 Nov;24 Suppl B:209-11. doi: 10.1093/jac/24.suppl_b.209.
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A comparison between amoxycillin/clavulanate and mezlocillin in abdominal surgical prophylaxis.
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J Antimicrob Chemother. 1988 Sep;22(3):363-9. doi: 10.1093/jac/22.3.363.
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A meta-analysis of the use of amoxycillin-clavulanic acid in surgical prophylaxis.阿莫西林-克拉维酸用于外科手术预防的荟萃分析。
J Hosp Infect. 1992 Nov;22 Suppl A:9-21. doi: 10.1016/s0195-6701(05)80003-9.
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Amoxycillin-clavulanic acid (Augmentin) versus metronidazole as prophylaxis in hysterectomy: a prospective randomized clinical trial.阿莫西林-克拉维酸(奥格门汀)与甲硝唑在子宫切除术中作为预防用药的比较:一项前瞻性随机临床试验。
Br J Obstet Gynaecol. 1988 Sep;95(9):951. doi: 10.1111/j.1471-0528.1988.tb06589.x.
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Amoxicillin-clavulanate prophylaxis against wound infections after clean-contaminated surgery. A controlled, randomized, prospective study.阿莫西林-克拉维酸预防清洁-污染手术后伤口感染。一项对照、随机、前瞻性研究。
Eur J Surg. 1991 Apr;157(4):271-5.
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Ceftriaxone versus clavulanate-potentiated amoxycillin for prophylaxis against post-operative sepsis in biliary surgery: a prospective randomized study in 200 patients.头孢曲松与克拉维酸增强型阿莫西林用于预防胆道手术术后脓毒症的比较:一项针对200例患者的前瞻性随机研究。
Curr Med Res Opin. 1989;11(6):354-9. doi: 10.1185/03007998909110135.
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Prophylaxis in gynaecological surgery: a prospective randomized comparison between single dose prophylaxis with amoxycillin/clavulanate and the combination of cefuroxime and metronidazole.妇科手术中的预防措施:阿莫西林/克拉维酸单剂量预防与头孢呋辛和甲硝唑联合使用的前瞻性随机比较。
J Antimicrob Chemother. 1989 Nov;24 Suppl B:213-6. doi: 10.1093/jac/24.suppl_b.213.
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Amoxycillin-clavulanic acid (Augmentin) versus metronidazole as prophylaxis in hysterectomy: a prospective, randomized clinical trial.阿莫西林-克拉维酸(奥格门汀)与甲硝唑在子宫切除术中的预防性应用:一项前瞻性随机临床试验。
Br J Obstet Gynaecol. 1988 Mar;95(3):286-93. doi: 10.1111/j.1471-0528.1988.tb06871.x.

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The cost effectiveness of amoxicillin/clavulanic acid as antibacterial prophylaxis in abdominal and gynaecological surgery.
阿莫西林/克拉维酸在腹部及妇科手术中作为抗菌预防用药的成本效益
Pharmacoeconomics. 1995 Apr;7(4):347-56. doi: 10.2165/00019053-199507040-00008.