妇科手术中的预防措施：阿莫西林/克拉维酸单剂量预防与头孢呋辛和甲硝唑联合使用的前瞻性随机比较。
Prophylaxis in gynaecological surgery: a prospective randomized comparison between single dose prophylaxis with amoxycillin/clavulanate and the combination of cefuroxime and metronidazole.
作者信息
Friese S, Willems F T, Loriaux S M, Meewis J M
机构信息
Department of Obstetrics and Gynaecology, Stichting Ignatius Ziekenhuis, Breda, The Netherlands.
出版信息
J Antimicrob Chemother. 1989 Nov;24 Suppl B:213-6. doi: 10.1093/jac/24.suppl_b.213.
A prospective randomized comparison of a single pre-operative dose of 2.2 g amoxycillin/clavulanate versus the combination of 1.5 g cefuroxime plus 0.5 g metronidazole was conducted in 467 women, who underwent gynaecological surgery. The incidence of febrile morbidity, urinary tract infection, wound infection and the use of post-operative antimicrobial agents was similar in the two groups. Amoxycillin/clavulanate is as effective as a combination of cefuroxime and metronidazole and less expensive.
对467名接受妇科手术的女性进行了一项前瞻性随机对照研究，比较术前单次给予2.2克阿莫西林/克拉维酸盐与1.5克头孢呋辛加0.5克甲硝唑联合用药的效果。两组的发热性疾病、尿路感染、伤口感染发生率以及术后抗菌药物的使用情况相似。阿莫西林/克拉维酸盐与头孢呋辛和甲硝唑联合用药同样有效，且成本更低。
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