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糖尿病酮症酸中毒过程中的视神经与脑水肿

Optic Nerve and Cerebral Edema in the Course of Diabetic Ketoacidosis.

作者信息

Szmygel Łukasz, Kosiak Wojciech, Zorena Katarzyna, Myśliwiec Małgorzata

机构信息

Clinic of Pediatrics Diabetology and Endocrinology, Medical University of Gdansk, 80-952 Gdansk, Poland.

出版信息

Curr Neuropharmacol. 2016;14(8):784-791. doi: 10.2174/1570159x14666160225155151.

Abstract

In the recent years we have been observing an increased incidence of type 1 diabetes in children and adolescents. This leads to a more frequent acute complication of type 1 diabetes among children with hyperglycemia. The most common of these is diabetic ketoacidosis (DKA), while cerebral edema is the most dangerous. In children with DKA, cerebral edema most often presents with clinical symptoms but may also appear in the so-called "subclinical" form. That is why the search continues for new methods of assessing and monitoring cerebral edema in the course of DKA treatment. Ultrasonographic optic nerve sheath diameter (US ONSD) assessment is performed in various clinical scenarios when cerebral edema is suspected. It is most often performed in adult patients but increasingly often in children. US ONSD assessment is useful in the treatment of DKA in children with type 1 diabetes. This manuscript provides an overview of research results available in PubMed and other available databases on the course of treatment of DKA in children with type 1 diabetes.

摘要

近年来,我们观察到儿童和青少年1型糖尿病的发病率有所上升。这导致高血糖儿童中1型糖尿病的急性并发症更为频繁。其中最常见的是糖尿病酮症酸中毒(DKA),而脑水肿是最危险的。在患有DKA的儿童中,脑水肿最常表现为临床症状,但也可能以所谓的“亚临床”形式出现。这就是为什么在DKA治疗过程中仍在继续寻找评估和监测脑水肿的新方法。当怀疑有脑水肿时,在各种临床情况下都会进行超声视神经鞘直径(US ONSD)评估。它最常在成年患者中进行,但在儿童中也越来越常见。US ONSD评估对1型糖尿病儿童的DKA治疗很有用。本手稿概述了在PubMed和其他可用数据库中可获得的关于1型糖尿病儿童DKA治疗过程的研究结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d2e/5333594/6bd66c9ad0da/CN-14-784_F1.jpg

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