Acer Semra, Ağladıoğlu Sebahat Yılmaz, Pekel Gökhan, Özhan Bayram, Çetin Ebru Nevin, Yağcı Ramazan, Yıldırım Cem
Department of Ophthalmology, Pamukkale University, Kinikli Kampusu, Denizli, Turkey.
Department of Pediatric Endocrinology, Pamukkale University, Kinikli Kampusu, Denizli, Turkey.
J AAPOS. 2016 Feb;20(1):54-7. doi: 10.1016/j.jaapos.2015.10.008.
To compare crystalline lens density in obese and nonobese children.
A total of 40 obese (25 females) and 46 age-sex matched controls (26 females) were included in this prospective study. Children with ocular diseases (except for mild refractive errors), ocular trauma, or surgery and any systemic disorders, including diabetes, were excluded. Lens densitometry (LD), central corneal thickness (CCT), anterior chamber depth (ACD) and corneal volume (CV) were measured by Pentacam HR.
Mean participant age was 12.0 ± 1.9 (range, 7.2-18 years) in the obese group and 11.7 ± 2.0 (range, 7.5-16.1 years) in the control group. The BMI was 29.9 ± 4.5 in the obese group and 18.7 ± 2.5 in the control group (P ≤ 0.05). The vertical, horizontal, and areal lens density measurements were higher in obese group than in controls (P ≤ 0.05). There was a positive correlation between BMI and vertical, horizontal, and areal lens density measurements. The difference in CCT, ACD, and CV was not statistically significant between groups (P ≥ 0.05).
There is increased lens density in the obese children compared with controls. Pentacam HR may provide objective data about lens density in children.
比较肥胖儿童与非肥胖儿童的晶状体密度。
本前瞻性研究共纳入40名肥胖儿童（25名女性）和46名年龄及性别匹配的对照儿童（26名女性）。排除患有眼部疾病（轻度屈光不正除外）、眼外伤、手术或任何全身性疾病（包括糖尿病）的儿童。使用Pentacam HR测量晶状体密度（LD）、中央角膜厚度（CCT）、前房深度（ACD）和角膜体积（CV）。
肥胖组参与者的平均年龄为12.0 ± 1.9岁（范围7.2 - 18岁），对照组为11.7 ± 2.0岁（范围7.5 - 16.1岁）。肥胖组的BMI为29.9 ± 4.5，对照组为18.7 ± 2.5（P≤0.05）。肥胖组的晶状体垂直、水平和面积密度测量值均高于对照组（P≤0.05）。BMI与晶状体垂直、水平和面积密度测量值呈正相关。两组之间CCT、ACD和CV的差异无统计学意义（P≥0.05）。
与对照组相比，肥胖儿童的晶状体密度增加。Pentacam HR可为儿童晶状体密度提供客观数据。
