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TTFields: where does all the skepticism come from?

作者信息

Wick Wolfgang

机构信息

Neurology Clinic, University of Heidelberg and Clinical Cooperation Unit (CCU) Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany (W.W.).

出版信息

Neuro Oncol. 2016 Mar;18(3):303-5. doi: 10.1093/neuonc/now012.

DOI:10.1093/neuonc/now012
PMID:26917587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4767251/
Abstract
摘要

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本文引用的文献

1
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.替莫唑胺联合肿瘤电场治疗与替莫唑胺单药治疗胶质母细胞瘤的维持治疗：一项随机临床试验。
JAMA. 2015 Dec 15;314(23):2535-43. doi: 10.1001/jama.2015.16669.
2
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.西仑吉肽联合标准治疗用于伴有 MGMT 启动子甲基化的新诊断胶质母细胞瘤患者（CENTRIC EORTC 26071-22072 研究）：一项多中心、随机、开放标签、3 期临床试验。
Lancet Oncol. 2014 Sep;15(10):1100-8. doi: 10.1016/S1470-2045(14)70379-1. Epub 2014 Aug 19.
3
MGMT testing--the challenges for biomarker-based glioma treatment.MGMT 检测——基于生物标志物的脑胶质瘤治疗面临的挑战。
Nat Rev Neurol. 2014 Jul;10(7):372-85. doi: 10.1038/nrneurol.2014.100. Epub 2014 Jun 10.
4
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.贝伐珠单抗联合放疗-替莫唑胺治疗新诊断的胶质母细胞瘤。
N Engl J Med. 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345.
5
A randomized trial of bevacizumab for newly diagnosed glioblastoma.贝伐珠单抗治疗新诊断的胶质母细胞瘤的随机试验。
N Engl J Med. 2014 Feb 20;370(8):699-708. doi: 10.1056/NEJMoa1308573.
6
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.替莫唑胺剂量密集疗法治疗新诊断的胶质母细胞瘤：一项随机 III 期临床试验。
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7
NovoTTF-100A versus physician's choice chemotherapy in recurrent glioblastoma: a randomised phase III trial of a novel treatment modality.NovoTTF-100A 与医师选择化疗治疗复发性胶质母细胞瘤的比较：一种新型治疗方式的随机 III 期试验。
Eur J Cancer. 2012 Sep;48(14):2192-202. doi: 10.1016/j.ejca.2012.04.011. Epub 2012 May 18.
8
Early palliative care for patients with metastatic non-small-cell lung cancer.转移性非小细胞肺癌患者的早期姑息治疗。
N Engl J Med. 2010 Aug 19;363(8):733-42. doi: 10.1056/NEJMoa1000678.
9
Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors.交变电场可抑制动物肿瘤模型和人类脑肿瘤中的细胞增殖。
Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10152-7. doi: 10.1073/pnas.0702916104. Epub 2007 Jun 5.
10
MGMT gene silencing and benefit from temozolomide in glioblastoma.MGMT基因沉默与胶质母细胞瘤对替莫唑胺的获益
N Engl J Med. 2005 Mar 10;352(10):997-1003. doi: 10.1056/NEJMoa043331.