Srinivasan H
Lepr Rev. 1989 Dec;60(4):278-82. doi: 10.5935/0305-7518.19890035.
The assumptions underlying trials of agents claiming to heal plantar ulcers 'faster' and 'better' are shown to be fallacious and it is pointed out that in most cases these ulcers fail to heal for lack of attention and not for want of a specific topical agent. Clinical trials in this area are difficult and are not worth the trouble as they do not add to our knowledge about these ulcers or their management in the clinic or in the field.
那些声称能“更快”“更好”治愈足底溃疡的药物试验所依据的假设被证明是错误的,并且指出在大多数情况下,这些溃疡未能愈合是因为缺乏关注,而非缺少某种特定的局部用药。该领域的临床试验困难重重,且不值得去做,因为它们并未增加我们对这些溃疡或其在临床及实际应用中治疗方法的了解。