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[四氯十氧化合物对氧分压的升高及伤口愈合的促进作用]

[Increase of oxygen partial pressure and acceleration of wound healing by tetrachlorodecaoxide].

作者信息

Weiler-Mithoff E M, Friederich H C, Horn W, Issing K

机构信息

Medizinisches Zentrum für Hautkrankheiten, Abteilung für Haut-und Geschlechtskrankheiten der Philipps-Universität, Marburg.

出版信息

Z Hautkr. 1989 Mar 15;64(3):208-11.

PMID:2718552
Abstract

63 transcutaneous measurements of oxygen pressure and 36 series of infrared thermograms in 9 hypoxic wounds showed that topical administration of tetrachlorine decaoxide (TCDO) results in increased oxygen supply of the wound. This effect is associated with improvement of the skin temperature and decrease of the pathological temperature difference between the wound and the surrounding tissue. TCDO can induce physiological wound healing, since it improves the mechanisms of the immune defence system, wound cleansing, granulation, and epithelialization in slow-healing wounds.

摘要

对9个缺氧伤口进行的63次经皮氧压测量和36组红外热像图显示,局部应用四氯十氧化物(TCDO)可增加伤口的氧气供应。这种作用与皮肤温度的改善以及伤口与周围组织之间病理温差的减小有关。TCDO可诱导生理性伤口愈合,因为它改善了免疫防御系统、伤口清洁、肉芽形成和上皮形成等机制,这些机制在愈合缓慢的伤口中发挥作用。

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