Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
J Geriatr Cardiol. 2016 Jan;13(1):31-6. doi: 10.11909/j.issn.1671-5411.2016.01.004.
To investigate the procedural outcomes and the long-term survival of patients undergoing transcatheter aortic valve implantation (TAVI) and compare study results of patients ≤ 80 years and patients > 80 years old.
A total of 240 patients treated with TAVI were divided into two groups according to age ≤ 80 years (n = 105; 43.8%) and > 80 years (n = 135; 56.2%). The baseline characteristics and the procedural outcomes were compared between these two groups of patients.
With the exception of peripheral artery disease and hypercholesterolemia, which were more frequently observed in the older age group, baseline characteristics were comparable between groups. Complication rates did not differ significantly between patients ≤ 80 years and patients > 80 years. There were no differences in 30-day mortality rates between patients aged ≤ 80 years and patients > 80 years old (9.5% vs. 7.4%, respectively; P = 0.557). After a median follow-up of 28 months (interquartile range: 16-42 months), 50 (47.6%) patients aged ≤ 80 years died compared to 57 (42%) deaths in the group of patients > 80 years old (P = 0.404).
The results of the present single center study showed that age did not significantly impact the outcomes of TAVI.
研究行经导管主动脉瓣植入术（TAVI）患者的手术结果和长期生存率，并比较≤80 岁和>80 岁患者的研究结果。
根据年龄将 240 例行 TAVI 治疗的患者分为两组，≤80 岁组（n=105；43.8%）和>80 岁组（n=135；56.2%）。比较两组患者的基线特征和手术结果。
除外周动脉疾病和高胆固醇血症在高龄组更为常见外，两组患者的基线特征无显著差异。两组患者的并发症发生率无显著差异。≤80 岁组和>80 岁组患者的 30 天死亡率分别为 9.5%和 7.4%（P=0.557），差异无统计学意义。中位随访 28 个月（四分位距：16-42 个月）后，≤80 岁组 50 例（47.6%）患者死亡，而>80 岁组 57 例（42%）患者死亡（P=0.404）。
本单中心研究结果表明，年龄对 TAVI 结局无显著影响。
