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一例喉癌合并皮肌炎病例

A Case of Laryngeal Cancer Associated with Dermatomyositis.

作者信息

Kusunoki Takeshi, Homma Hirotomo, Kidokoro Yoshinobu, Yanai Aya, Ikeda Katsuhisa, Wada Ryo

机构信息

Department of Otorhinolaryngology, Juntendo University of Medicine , Shizuoka Hospital.

Department of Otorhinolaryngology, Juntendo University of Medicine , Faculty of Medicine.

出版信息

Clin Pract. 2015 Dec 22;5(4):818. doi: 10.4081/cp.2015.818. eCollection 2015 Nov 5.

DOI:10.4081/cp.2015.818
PMID:26918103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4745597/
Abstract

We experienced a rare case of laryngeal cancer associated with dermatomyositis. The patient was a 63-year-old male and Japanese. He was admitted to our department of Otorhinolaryngology with dysphagia for a day as a chief complaint. He became aware of hoarseness with bloody sputum and then face edema with redness a half year before. At first physical examination, he had bilateral eyelid edema with erythema, finger edema with keratinizing erythema and limb extensor erythema. Serous creatine phosphokinase was 850 IU/mL (normal range: 40-200 IU/mL). Later, he was referred to the rheumatology department and was diagnosed as having dermatomyositis. Fiberscopic examination revealed laryngeal cancer with left laryngeal palsy. We gave priority to the laryngeal treatment. As a result, the symptoms of dermatomyositis were improved.

摘要

我们遇到了一例罕见的喉癌合并皮肌炎病例。患者为一名63岁的日本男性。他因吞咽困难一天为主诉入住我们的耳鼻喉科。半年前他开始出现声音嘶哑伴咯血痰,随后面部水肿伴发红。初次体格检查时,他有双侧眼睑水肿伴红斑、手指水肿伴角化性红斑以及四肢伸侧红斑。血清肌酸磷酸激酶为850 IU/mL(正常范围:40 - 200 IU/mL)。后来,他被转诊至风湿科,被诊断为皮肌炎。纤维镜检查显示喉癌伴左侧喉麻痹。我们优先进行了喉部治疗。结果,皮肌炎的症状得到了改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb83/4745597/108fd3c94c71/cp-2015-4-818-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb83/4745597/a34aca63e787/cp-2015-4-818-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb83/4745597/bc0d61dd1e9e/cp-2015-4-818-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb83/4745597/108fd3c94c71/cp-2015-4-818-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb83/4745597/a34aca63e787/cp-2015-4-818-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb83/4745597/bc0d61dd1e9e/cp-2015-4-818-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb83/4745597/108fd3c94c71/cp-2015-4-818-g003.jpg

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本文引用的文献

1
Dermatomyositis and malignancy: a retrospective study of 115 cases.皮肌炎与恶性肿瘤:115例回顾性研究
Eur Rev Med Pharmacol Sci. 2009 Mar-Apr;13(2):77-80.
2
Identification of autoantibodies elicited in a patient with prostate cancer presenting as dermatomyositis.在一名表现为皮肌炎的前列腺癌患者中引发的自身抗体的鉴定。
Int J Urol. 2006 Mar;13(3):211-7. doi: 10.1111/j.1442-2042.2006.01263.x.
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Predicting factors of malignancy in dermatomyositis and polymyositis: a case-control study.皮肌炎和多发性肌炎恶性肿瘤的预测因素:一项病例对照研究。
Br J Dermatol. 2001 Apr;144(4):825-31. doi: 10.1046/j.1365-2133.2001.04140.x.
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Cricopharyngeal myotomy in the treatment of dysphagia.环咽肌切开术治疗吞咽困难
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