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[腹内及腹膜后肉瘤]

[Intra-abdominal and retroperitoneal sarcomas].

作者信息

Kirchberg J, Weitz J

机构信息

Klinik und Poliklinik für Viszeral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.

出版信息

Chirurg. 2016 Mar;87(3):255-66; quiz 267. doi: 10.1007/s00104-016-0156-7.

DOI:10.1007/s00104-016-0156-7
PMID:26920140
Abstract

Sarcomas are a heterogeneous group of rare tumors that originate from mesenchymal tissue. Radical R0 resection is the only curative option, which is especially challenging in retroperitoneal or intra-abdominal sarcomas. This article describes the current data on optimal interdisciplinary and primarily surgical therapy of visceral sarcomas. Surgical resection of retroperitoneal sarcomas must be performed according to the principle of radical compartmental resection, i.e. with complete excision of the mass along with en bloc visceral resection of adjacent organs and tissues covering the tumor, which also contains any not obviously infiltrated neighboring organs. The main objective is R0 resection without opening the tumor capsule in the primary operation because the best long-term results can be achieved with this approach.

摘要

肉瘤是一组起源于间叶组织的罕见异质性肿瘤。根治性R0切除是唯一的治愈选择,这在腹膜后或腹腔内肉瘤中尤其具有挑战性。本文介绍了关于内脏肉瘤最佳多学科及主要手术治疗的当前数据。腹膜后肉瘤的手术切除必须按照根治性分区切除原则进行,即完整切除肿块,并整块切除覆盖肿瘤的相邻器官和组织,包括任何未明显受浸润的邻近器官。主要目标是在初次手术中不打开肿瘤包膜进行R0切除,因为采用这种方法可取得最佳长期效果。

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[Intra-abdominal and retroperitoneal sarcomas].[腹内及腹膜后肉瘤]
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Adjuvant Imatinib for High-Risk GI Stromal Tumor: Analysis of a Randomized Trial.辅助伊马替尼治疗高危胃肠道间质瘤:一项随机试验分析。
J Clin Oncol. 2016 Jan 20;34(3):244-50. doi: 10.1200/JCO.2015.62.9170. Epub 2015 Nov 2.
2
Outcome following resection of retroperitoneal sarcoma.腹膜后肉瘤切除术后的结果。
Br J Surg. 2015 Dec;102(13):1698-709. doi: 10.1002/bjs.9934. Epub 2015 Sep 23.
3
Impact of chemotherapy on survival in surgically resected retroperitoneal sarcoma.化疗对手术切除的腹膜后肉瘤患者生存的影响。
Eur J Surg Oncol. 2015 Oct;41(10):1386-92. doi: 10.1016/j.ejso.2015.07.014. Epub 2015 Jul 29.
4
Current management of gastrointestinal stromal tumors: Surgery, current biomarkers, mutations, and therapy.胃肠道间质瘤的当前管理:手术、当前生物标志物、突变及治疗
Surgery. 2015 Nov;158(5):1149-64. doi: 10.1016/j.surg.2015.06.027. Epub 2015 Aug 1.
5
Analysis of perioperative radiation therapy in the surgical treatment of primary and recurrent retroperitoneal sarcoma.原发性和复发性腹膜后肉瘤手术治疗中围手术期放射治疗的分析
J Surg Oncol. 2015 Sep;112(4):352-8. doi: 10.1002/jso.23996. Epub 2015 Aug 4.
6
Post-operative renal function following nephrectomy as part of en bloc resection of retroperitoneal sarcoma (RPS).作为腹膜后肉瘤(RPS)整块切除一部分的肾切除术后的肾功能。
J Surg Oncol. 2015 Jul;112(1):98-102. doi: 10.1002/jso.23949. Epub 2015 Jul 14.
7
Comparison of Perioperative Radiation Therapy and Surgery Versus Surgery Alone in 204 Patients With Primary Retroperitoneal Sarcoma: A Retrospective 2-Institution Study.204例原发性腹膜后肉瘤患者围手术期放疗与手术联合与单纯手术的比较:一项回顾性双机构研究
Ann Surg. 2015 Jul;262(1):156-62. doi: 10.1097/SLA.0000000000001063.
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Long-term morbidity after multivisceral resection for retroperitoneal sarcoma.腹膜后肉瘤的多脏器切除术后长期发病率。
Br J Surg. 2015 Aug;102(9):1079-87. doi: 10.1002/bjs.9829. Epub 2015 Jun 3.
9
GI Stromal Tumors: 15 Years of Lessons From a Rare Cancer.胃肠道间质瘤:一种罕见癌症 15 年的经验教训。
J Clin Oncol. 2015 Jun 1;33(16):1849-54. doi: 10.1200/JCO.2014.59.7344. Epub 2015 Apr 27.
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Histology-based Classification Predicts Pattern of Recurrence and Improves Risk Stratification in Primary Retroperitoneal Sarcoma.基于组织学的分类可预测原发性腹膜后肉瘤的复发模式并改善风险分层。
Ann Surg. 2016 Mar;263(3):593-600. doi: 10.1097/SLA.0000000000001149.