• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

What is synergy?

作者信息

Berenbaum M C

机构信息

Department of Experimental Pathology, St. Mary's Hospital Medical School, London, United Kingdom.

出版信息

Pharmacol Rev. 1989 Jun;41(2):93-141.

PMID:2692037
Abstract
摘要

相似文献

1
What is synergy?什么是协同作用?
Pharmacol Rev. 1989 Jun;41(2):93-141.
2
Combined effect of multiple carcinogens and synergy index.
J Theor Biol. 2006 Nov 7;243(1):143-51. doi: 10.1016/j.jtbi.2006.05.027. Epub 2006 Jun 7.
3
Principles: mechanisms and modeling of synergism in cellular responses.
Trends Pharmacol Sci. 2005 Oct;26(10):526-32. doi: 10.1016/j.tips.2005.08.003.
4
Drug synergy in experimental African trypanosomiasis.
Tropenmed Parasitol. 1982 Jun;33(2):76-82.
5
Simple designs and model-free tests for synergy.用于协同作用的简单设计和无模型测试。
Biometrics. 1994 Sep;50(3):834-41.
6
The search for synergy: a critical review from a response surface perspective.协同作用的探索:基于响应面视角的批判性综述
Pharmacol Rev. 1995 Jun;47(2):331-85.
7
In vivo synergy of vitamin K3 and methotrexate in tumor-bearing animals.
Cancer Treat Rep. 1986 Dec;70(12):1433-5.
8
Synergism between insecticides permethrin and propoxur occurs through activation of presynaptic muscarinic negative feedback of acetylcholine release in the insect central nervous system.氯菊酯和残杀威之间的协同作用是通过激活昆虫中枢神经系统中乙酰胆碱释放的突触前毒蕈碱负反馈来实现的。
Neurotoxicology. 2006 Jul;27(4):508-19. doi: 10.1016/j.neuro.2006.01.011. Epub 2006 Mar 3.
9
The concentration-dependent nature of in vitro amphotericin B-itraconazole interaction against Aspergillus fumigatus: isobolographic and response surface analysis of complex pharmacodynamic interactions.两性霉素B与伊曲康唑体外联合抗烟曲霉的浓度依赖性相互作用:复杂药效学相互作用的等效应线图和响应面分析
Int J Antimicrob Agents. 2006 Nov;28(5):439-49. doi: 10.1016/j.ijantimicag.2006.07.011. Epub 2006 Oct 19.
10
Measurement of the potencies of drug mixtures.药物混合物效力的测定。
Biometrics. 1969 Sep;25(3):477-87.

引用本文的文献

1
Claudin-1 Contributes to Gastrointestinal Stromal Tumors (GIST) Resistance to Imatinib Mesylate (IM) via Regulation of FGFR-Signaling.Claudin-1通过调节FGFR信号通路导致胃肠道间质瘤(GIST)对甲磺酸伊马替尼(IM)耐药。
Int J Mol Sci. 2025 Aug 22;26(17):8138. doi: 10.3390/ijms26178138.
2
Identifying Drug Combination Strategies for Fusion Positive Leukemia.确定融合阳性白血病的联合用药策略
Precis Oncogenom. 2025 Jul 16. doi: 10.1080/28354311.2025.2530229.
3
Targeting the p53/xCT/GSH Axis with PRIMA-1 Combined with Sulfasalazine Shows Therapeutic Potential in Chronic Lymphocytic Leukemia.
PRIMA-1联合柳氮磺胺吡啶靶向p53/xCT/谷胱甘肽轴在慢性淋巴细胞白血病中显示出治疗潜力。
Int J Mol Sci. 2025 Jun 10;26(12):5559. doi: 10.3390/ijms26125559.
4
Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies.BMS-986408的发现,一种首创的双重二酰甘油激酶α和二酰甘油激酶ζ抑制剂,可释放PD-1免疫检查点和嵌合抗原受体T细胞免疫疗法。
Cancer Immunol Res. 2025 Sep 2;13(9):1342-1362. doi: 10.1158/2326-6066.CIR-25-0156.
5
How to predict effective drug combinations - moving beyond synergy scores.如何预测有效的药物组合——超越协同分数
iScience. 2025 May 9;28(6):112622. doi: 10.1016/j.isci.2025.112622. eCollection 2025 Jun 20.
6
Integrative transcriptome-based drug repurposing in tuberculosis.基于整合转录组学的结核病药物再利用研究
bioRxiv. 2025 Jun 2:2025.06.02.657296. doi: 10.1101/2025.06.02.657296.
7
SynDRep: a synergistic partner prediction tool based on knowledge graph for drug repurposing.SynDRep:一种基于知识图谱的药物重定向协同伙伴预测工具。
Bioinform Adv. 2025 Jun 5;5(1):vbaf092. doi: 10.1093/bioadv/vbaf092. eCollection 2025.
8
MADSP: predicting anti-cancer drug synergy through multi-source integration and attention-based representation learning.MADSP:通过多源整合和基于注意力的表征学习预测抗癌药物协同作用
Bioinformatics. 2025 Jun 2;41(6). doi: 10.1093/bioinformatics/btaf326.
9
Combinatorial Effects of Free and Nanoencapsulated Forms of Cabazitaxel and RAS-Selective Lethal 3 in Breast Cancer Cells.卡巴他赛游离形式与纳米包封形式以及RAS选择性致死因子3在乳腺癌细胞中的联合效应
Pharmaceutics. 2025 May 17;17(5):657. doi: 10.3390/pharmaceutics17050657.
10
In Vitro Activity of Imipenem/Relebactam Alone and in Combination Against Cystic Fibrosis Isolates of .亚胺培南/瑞来巴坦单独及联合使用对囊性纤维化分离株的体外活性 。 你提供的原文似乎不完整,句末“. ”后面应该还有具体内容。
Antibiotics (Basel). 2025 May 10;14(5):486. doi: 10.3390/antibiotics14050486.