Hauschild Daniela Barbieri, Barbosa Eliana, Moreira Emilia Addison Machado, Ludwig Neto Norberto, Platt Vanessa Borges, Piacentini Filho Eduardo, Wazlawik Elisabeth, Moreno Yara Maria Franco
Department of Nutrition and Postgraduate Program in Nutrition, Federal University of Santa Catarina, Florianópolis, Brazil.
Joana de Gusmão Children's Hospital, Florianópolis, Brazil.
Nutr Clin Pract. 2016 Jun;31(3):378-86. doi: 10.1177/0884533615627157. Epub 2016 Feb 26.
(1) To compare nutrition and hydration status between a group of children/adolescents with cystic fibrosis (CFG; n = 46; median age, 8.5 years) and a control group without cystic fibrosis (CG). (2) To examine the association of nutrition and hydration status with lung function in the CFG.
A cross-sectional study. Nutrition screening, anthropometric parameters, and bioelectrical impedance analysis (BIA) were assessed. The z scores for body mass index for age, height for age, mid upper arm circumference, triceps and subscapular skinfold thickness, mid upper arm muscle area, resistance/height, and reactance/height were calculated. Bioelectrical impedance vector analysis was conducted. Forced expiratory volume in 1 second <80% was considered lung function impairment. An adjusted logistic regression was applied (P < .05).
In the CFG, lung function impairment was observed in 51.1%. All anthropometric parameters were lower, and the mean z-resistance/height and z-reactance/height were higher in the CFG (P < .05) compared with the CG. In the CFG, 43% were severely/mildly dehydrated, while none were in the CG (P = .007). In the CFG, there was an association between high nutrition risk-via nutrition screening (odds ratio [OR], 22.28; P < .05), lower values of anthropometric parameters, higher z-resistance/height (OR, 2.23; P < .05) and z-reactance/height (OR, 1.81; P < .05), and dehydration (OR, 4.94; P < .05)-and lung function impairment.
The CFG exhibited a compromised nutrition status assessed by anthropometric and BIA parameters. Nutrition screening, anthropometric and BIA parameters, and hydration status were associated with lung function.
（1）比较一组患有囊性纤维化的儿童/青少年（CFG；n = 46；中位年龄8.5岁）与一组无囊性纤维化的对照组（CG）之间的营养和水合状态。（2）研究CFG中营养和水合状态与肺功能的关联。
一项横断面研究。评估营养筛查、人体测量参数和生物电阻抗分析（BIA）。计算年龄别体重指数、年龄别身高、上臂中部周长、肱三头肌和肩胛下皮褶厚度、上臂中部肌肉面积、电阻/身高和电抗/身高的z评分。进行生物电阻抗矢量分析。一秒用力呼气量<80%被视为肺功能损害。应用校正逻辑回归（P <.05）。
在CFG组中，51.1%观察到肺功能损害。与CG组相比，CFG组所有人体测量参数均较低，平均z电阻/身高和z电抗/身高较高（P <.05）。在CFG组中，43%为重度/轻度脱水，而CG组无一人脱水（P =.007）。在CFG组中，通过营养筛查得出的高营养风险（比值比[OR]，22.28；P <.05）、人体测量参数值较低、较高的z电阻/身高（OR，2.23；P <.05）和z电抗/身高（OR，1.81；P <.05）以及脱水（OR，4.94；P <.05）与肺功能损害之间存在关联。
通过人体测量和BIA参数评估，CFG组的营养状况受损。营养筛查、人体测量和BIA参数以及水合状态与肺功能相关。
