Vleugels M P, Brabin B, Eling W M, de Graaf R
St Joseph Hospital, Department of Obstetrics and Gynaecology, Eindhoven, The Netherlands.
Trans R Soc Trop Med Hyg. 1989 Mar-Apr;83(2):173-7. doi: 10.1016/0035-9203(89)90632-9.
Women living under holoendemic conditions of malaria in Kenya exhibited an increased prevalence of clinical malaria during pregnancy. In addition parasite rate and density were higher in primigravidae compared to multigravidae. Higher serum cortisol concentrations were found in women with patent malaria during pregnancy and the levels were higher before, during and after the malaria episode. A causal relation between serum cortisol levels and suppression of malaria immunity during pregnancy is discussed.
生活在肯尼亚疟疾高度流行地区的妇女在孕期临床疟疾的患病率有所上升。此外，初产妇的寄生虫感染率和密度高于经产妇。孕期患显性疟疾的妇女血清皮质醇浓度更高，且在疟疾发作前、发作期间和发作后浓度均较高。本文讨论了血清皮质醇水平与孕期疟疾免疫力抑制之间的因果关系。
