Page Martin, MacLean Dan, Schudoma Christian
Bioinformatics Group, The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
Triticeae Genomics Group, The Genome Analysis Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
BMC Res Notes. 2016 Feb 27;9:130. doi: 10.1186/s13104-016-1938-1.
To cope with the ever-increasing amount of sequence data generated in the field of genomics, the demand for efficient and fast database searches that drive functional and structural annotation in both large- and small-scale genome projects is on the rise. The tools of the BLAST+ suite are the most widely employed bioinformatic method for these database searches. Recent trends in bioinformatics application development show an increasing number of JavaScript apps that are based on modern frameworks such as Node.js. Until now, there is no way of using database searches with the BLAST+ suite from a Node.js codebase.
We developed blastjs, a Node.js library that wraps the search tools of the BLAST+ suite and thus allows to easily add significant functionality to any Node.js-based application.
blastjs is a library that allows the incorporation of BLAST+ functionality into bioinformatics applications based on JavaScript and Node.js. The library was designed to be as user-friendly as possible and therefore requires only a minimal amount of code in the client application. The library is freely available under the MIT license at https://github.com/teammaclean/blastjs.
为了应对基因组学领域生成的不断增加的序列数据量，在大规模和小规模基因组项目中推动功能和结构注释的高效快速数据库搜索的需求正在上升。BLAST+套件工具是这些数据库搜索中使用最广泛的生物信息学方法。生物信息学应用开发的最新趋势表明，基于Node.js等现代框架的JavaScript应用程序越来越多。到目前为止，还无法从Node.js代码库中使用BLAST+套件进行数据库搜索。
我们开发了blastjs，这是一个Node.js库，它封装了BLAST+套件的搜索工具，从而可以轻松地为任何基于Node.js的应用程序添加重要功能。
blastjs是一个允许将BLAST+功能集成到基于JavaScript和Node.js的生物信息学应用程序中的库。该库设计得尽可能用户友好，因此在客户端应用程序中只需要最少的代码量。该库在https://github.com/teammaclean/blastjs上根据MIT许可免费提供。
