School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom.
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia.
Mol Biol Evol. 2019 Dec 1;36(12):2922-2924. doi: 10.1093/molbev/msz185.
Comparing newly obtained and previously known nucleotide and amino-acid sequences underpins modern biological research. BLAST is a well-established tool for such comparisons but is challenging to use on new data sets. We combined a user-centric design philosophy with sustainable software development approaches to create Sequenceserver, a tool for running BLAST and visually inspecting BLAST results for biological interpretation. Sequenceserver uses simple algorithms to prevent potential analysis errors and provides flexible text-based and visual outputs to support researcher productivity. Our software can be rapidly installed for use by individuals or on shared servers.
比较新获得的和先前已知的核苷酸和氨基酸序列是现代生物学研究的基础。BLAST 是此类比较的成熟工具，但在新数据集上使用具有挑战性。我们结合以用户为中心的设计理念和可持续的软件开发方法创建了 Sequenceserver，这是一种用于运行 BLAST 并直观检查 BLAST 结果以进行生物学解释的工具。Sequenceserver 使用简单的算法来防止潜在的分析错误，并提供灵活的基于文本和可视化的输出，以支持研究人员的工作效率。我们的软件可以快速安装供个人或共享服务器使用。
