Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Department of Dermatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Curr Allergy Asthma Rep. 2016 Apr;16(4):26. doi: 10.1007/s11882-016-0605-x.
The diagnosis and treatment of mucosal disease with an allergic pathogenesis are challenging. Oral allergy is often a hypersensitivity reaction with variable symptoms and physical exam findings. Clinical diagnosis requires a history of prior allergen exposure, a delay from exposure to clinical findings, and improvement following allergen removal. The past decades have seen great contributions to the field of oral allergy. The aim of this review is to provide an approach to the diagnosis and treatment of oral dermatologic disease with a focus on diseases with an investigated allergic pathogenesis.
黏膜疾病的诊断和治疗具有挑战性,尤其是具有过敏发病机制的黏膜疾病。口腔过敏通常是一种变应性反应,具有不同的症状和体检结果。临床诊断需要有过敏原暴露史、从暴露到临床发现的延迟以及过敏原去除后的改善。过去几十年对口过敏领域做出了巨大贡献。本文的目的是提供一种方法来诊断和治疗口腔皮肤病,重点是研究过具有过敏发病机制的疾病。