Shroff Geeta
Stem Cell Therapy, Nutech Mediworld, New Delhi, India.
Am J Case Rep. 2016 Feb 29;17:124-8. doi: 10.12659/ajcr.896512.
Crohn's disease is a chronic inflammatory disease of the intestines, mainly the colon and ileum, related with ulcers and fistulae. It is estimated to affect 565,000 people in the United States. Currently available therapies, such as antibiotics, thiopurines, and anti-tumor necrosis factor-alpha agents, are only observed to reduce the complications associated with Crohn's disease and to improve quality of life, but cannot cure the disease. Stem cell therapy appears to have certain advantages over conventional therapies. Our study aimed to evaluate the efficacy of human embryonic stem cell therapy in a patient with Crohn's disease.
A 21-year-old male with chief complaints of intolerance to specific foods, abdominal pain, and diarrhea underwent human embryonic stem cell therapy for two months. After undergoing human embryonic stem cell therapy, the patient showed symptomatic relief. He had no complaints of back pain, abdominal pain, or diarrhea and had improved digestion. The patient had no signs and symptoms of skin infection, and had improved limb stamina, strength, and endurance. The condition of patient was stable after the therapy.
Human embryonic stem cell therapy might serve as a new optimistic treatment approach for Crohn's disease.
克罗恩病是一种肠道慢性炎症性疾病，主要累及结肠和回肠，与溃疡和瘘管有关。据估计，美国有56.5万人受其影响。目前可用的疗法，如抗生素、硫唑嘌呤和抗肿瘤坏死因子-α药物，仅观察到可减少与克罗恩病相关的并发症并改善生活质量，但无法治愈该疾病。干细胞疗法似乎比传统疗法具有某些优势。我们的研究旨在评估人胚胎干细胞疗法对一名克罗恩病患者的疗效。
一名21岁男性，主要症状为对特定食物不耐受、腹痛和腹泻，接受了两个月的人胚胎干细胞治疗。接受人胚胎干细胞治疗后，患者症状缓解。他没有背痛、腹痛或腹泻的主诉，消化功能有所改善。患者没有皮肤感染的体征和症状，肢体耐力、力量和耐力也有所提高。治疗后患者病情稳定。
人胚胎干细胞疗法可能是治疗克罗恩病的一种新的乐观治疗方法。
