Pizzi Laura T, Tran Judie, Shafa Anousheh, Waisbourd Michael, Hark Lisa, Murchison Ann P, Dai Yang, Mayro Eileen L, Haller Julia A
Thomas Jefferson University, 901 Walnut Street, Room 911, Philadelphia, PA, 19107, USA.
Wills Eye Hospital Glaucoma Research Center, 840 Walnut Street Suite 1140, Philadelphia, PA, USA.
Appl Health Econ Health Policy. 2016 Apr;14(2):229-40. doi: 10.1007/s40258-016-0231-8.
Glaucoma is the leadi ng cause of irreversible blindness in the USA. Glaucomatous vision loss is preventable with proper eye care, including appointment adherence. Therefore, interventions that improve appointment adherence can reduce the number of patients with more severe glaucoma.
The primary study aim was to determine the efficacy and cost-effectiveness of a multifaceted personal reminder intervention, which included a customized letter and personal telephone outreach, in improving appointment adherence of patients with glaucoma. A secondary study aim was to identify patient characteristics that were associated with non-adherence.
This prospective, randomized, controlled study included a cost-effectiveness analysis completed using a decision analytic model. The subjects included 256 patients with glaucoma. Study measures included appointment adherence and incremental cost effectiveness ratios.
Patients in the intervention group were more likely to adhere to appointments (82.31 vs. 69.05 %; RR 1.23; 95 % CI 1.04-1.37, p < 0.012) than patients in the usual care group. Patients in the intervention group were 23 % more likely to adhere to appointments (RR 1.23; 95 % CI 1.08-1.41, p < 0.0021) than patients in the usual care group, when adjusting for age, secondary insurance, primary open angle glaucoma diagnosis, number of previous visits at Wills Eye Hospital, and follow-up recommendation using Poisson regression. Per-patient cost of the program was US$11.32, and cost per follow-up attended within the adherence window was US$73.56.
A low cost reminder intervention consisting of a personalized letter and telephone outreach significantly improved appointment adherence of patients with glaucoma.
在美国,青光眼是导致不可逆失明的主要原因。通过适当的眼部护理,包括按时就诊,青光眼导致的视力丧失是可以预防的。因此,能够提高就诊依从性的干预措施可以减少患有更严重青光眼的患者数量。
主要研究目的是确定一种多方面的个人提醒干预措施(包括定制信件和个人电话随访)在提高青光眼患者就诊依从性方面的疗效和成本效益。次要研究目的是确定与不依从相关的患者特征。
这项前瞻性、随机、对照研究包括使用决策分析模型完成的成本效益分析。研究对象包括256例青光眼患者。研究指标包括就诊依从性和增量成本效益比。
与常规护理组患者相比,干预组患者更有可能按时就诊(82.31% 对 69.05%;相对风险 1.23;95% 置信区间 1.04 - 1.37,p < 0.012)。在调整年龄、二级保险、原发性开角型青光眼诊断、之前在威尔斯眼科医院的就诊次数以及使用泊松回归得出的随访建议后,干预组患者按时就诊的可能性比常规护理组患者高23%(相对风险 1.23;95% 置信区间 1.08 - 1.41,p < 0.0021)。该项目的人均成本为11.32美元,在依从性窗口内每次随访的成本为73.56美元。
由个性化信件和电话随访组成的低成本提醒干预措施显著提高了青光眼患者的就诊依从性。