N-杂环卡宾催化对醌甲基化物和富烯的1,6-氢膦酰化反应：一种合成不对称二芳基和三芳基甲基膦酸酯的原子经济性方法。
N-Heterocyclic carbene catalysed 1,6-hydrophosphonylation of p-quinone methides and fuchsones: an atom economical route to unsymmetrical diaryl- and triarylmethyl phosphonates.
作者信息
Arde Panjab, Vijaya Anand Ramasamy
机构信息
Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, Knowledge City, S. A. S. Nagar, Mohali, Manauli (PO), Punjab 140306, India.
出版信息
Org Biomol Chem. 2016 Jun 15;14(24):5550-4. doi: 10.1039/c6ob00289g.
A convenient organocatalytic approach to access unsymmetrical diaryl- and triarylmethyl phosphonates using NHC as a Brønsted base catalyst is described. This atom-economical protocol enables the installation of phosphonate groups on p-quinone methides and fuchsones through a 1,6-conjugate addition of dialkylphosphites, and the corresponding phosphonates were obtained in excellent yields.
描述了一种使用NHC作为布朗斯特碱催化剂来制备不对称二芳基和三芳基甲基膦酸酯的便捷有机催化方法。这种原子经济的方法能够通过亚磷酸二烷基酯的1,6-共轭加成将膦酸酯基团安装在对苯醌甲基化物和富烯上，并且以优异的产率获得相应的膦酸酯。
Zotero 插件