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植物磷酸肌醇信号传导——按需动态变化

Plant phosphoinositide signaling - dynamics on demand.

作者信息

Heilmann Ingo

机构信息

Department of Cellular Biochemistry, Institute for Biochemistry and Biotechnology, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle (Saale), Germany.

出版信息

Biochim Biophys Acta. 2016 Sep;1861(9 Pt B):1345-1351. doi: 10.1016/j.bbalip.2016.02.013. Epub 2016 Feb 24.

Abstract

Eukaryotic membranes contain small amounts of lipids with regulatory roles. An important class of such regulatory lipids are phosphoinositides (PIs). Within membranes, PIs serve as recruitment signals, as regulators of membrane protein function or as precursors for second messenger production, thereby influencing a multitude of cellular processes with key importance for plant function and development. Plant PIs occur locally and transiently within membrane microdomains, and their abundance is strictly controlled. To understand the functions of the plant PI-network it is important to understand not only downstream PI-effects, but also to identify and characterize factors contributing to dynamic PI formation. This article is part of a Special Issue entitled: Plant Lipid Biology edited by Kent D. Chapman and Ivo Feussner.

摘要

真核生物膜含有少量具有调节作用的脂质。这类重要的调节脂质是磷酸肌醇(PIs)。在膜内,PIs作为招募信号、膜蛋白功能的调节剂或第二信使产生的前体,从而影响许多对植物功能和发育至关重要的细胞过程。植物PIs在膜微区中局部且短暂地出现,其丰度受到严格控制。为了解植物PI网络的功能,不仅要了解PI的下游效应,还需要识别和表征有助于动态PI形成的因素。本文是由肯特·D·查普曼和伊沃·费斯纳编辑的特刊《植物脂质生物学》的一部分。

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