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建立急性肾损伤连续谱——利用数据源链接和长期随访追踪急性肾损伤:第15届急性透析质量倡议(ADQI)共识会议工作组声明

Establishing a continuum of acute kidney injury - tracing AKI using data source linkage and long-term follow-up: Workgroup Statements from the 15th ADQI Consensus Conference.

作者信息

Mehta Ravindra, Bihorac Azra, Selby Nicholas M, Quan Hude, Goldstein Stuart L, Kellum John A, Ronco Claudio, Bagshaw Sean M

机构信息

Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, CA USA.

Department of Anesthesiology, University of Florida, Box 100254, Gainesville, FL 32610-0254 USA.

出版信息

Can J Kidney Health Dis. 2016 Feb 26;3:13. doi: 10.1186/s40697-016-0102-0. eCollection 2016.

Abstract

BACKGROUND

Acute kidney injury (AKI) is independently associated with the development of chronic kidney disease, endstage kidney disease and increased all-cause and cardiovascular-specific mortality. The severity of the renal insult and the development of multiple AKI episodes increase the risk of occurrence of these outcomes. Despite these long-term effects, only a minority of patients receive nephrologist follow up after an episode of AKI; those that do may have improved outcomes. Furthermore, relatively simple quality improvement strategies have the potential to change this status quo.

METHODS

On this background, a working group of the 15(th) Acute Dialysis Quality Initiative (ADQI) conference applied the consensus-building process informed by review of English language articles identified through PubMed search to address questions related to the opportunities, methodological requirements and barriers for longitudinal follow-up of patients with AKI in the era of electronic health records and Big Data.

RESULTS

Four consensus statements answering the key questions identified by the working group are developed.

CONCLUSIONS

We have identified minimal data elements and potential data sources necessary to trace the natural history of patients from onset of AKI to long-term outcome. Minimum infrastructure and key barriers to achieving these goals are outlined together with proposed solutions.

摘要

背景

急性肾损伤(AKI)与慢性肾脏病、终末期肾病的发生以及全因死亡率和心血管疾病特异性死亡率的增加独立相关。肾脏损伤的严重程度以及多次急性肾损伤发作会增加这些不良后果发生的风险。尽管存在这些长期影响,但在急性肾损伤发作后,只有少数患者接受肾病专家的随访;接受随访的患者可能会有更好的预后。此外,相对简单的质量改进策略有可能改变这种现状。

方法

在此背景下,第15届急性透析质量倡议(ADQI)会议的一个工作组采用了通过PubMed搜索确定的英文文章综述所提供的共识建立过程,以解决与电子健康记录和大数据时代急性肾损伤患者纵向随访的机会、方法要求和障碍相关的问题。

结果

制定了四项共识声明,回答了工作组确定的关键问题。

结论

我们已经确定了追踪急性肾损伤患者从发病到长期预后自然病程所需的最少数据元素和潜在数据来源。概述了实现这些目标所需的最低基础设施和主要障碍,并提出了解决方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fed0/4768419/998c81f2d095/40697_2016_102_Fig1_HTML.jpg

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