Padeĭskaia E N
Antibiot Khimioter. 1989 Sep;34(9):657-62.
Derivatives of diaminopyrimidine as potentiators of the effect of the derivatives of sulfanilamide and other antibacterial drugs are discussed. Experimental data on sulfation, a new combined preparation, based on sulfamonomethoxine (a sulfanilamide derivative) and trimethoprim (a diaminopyrimidine derivative) are presented. Brief clinical characteristics of sulfation, its administration routes, doses, dosage advantages and better tolerance as compared to co-trimethoxazole+ (biseptol) are described.
讨论了二氨基嘧啶衍生物作为磺胺类药物和其他抗菌药物衍生物效果增强剂的情况。给出了基于磺胺间甲氧嘧啶(一种磺胺类药物衍生物)和甲氧苄啶(一种二氨基嘧啶衍生物)的新复方制剂“硫酸制剂”的实验数据。描述了“硫酸制剂”的简要临床特征、给药途径、剂量、剂量优势以及与复方新诺明(百炎净)相比更好的耐受性。