Serov V V
Arkh Patol. 1989;51(10):3-10.
The proofs of the heterogeneity of both the amyloid fiber protein and its precursor (serum and local) are, in the author's opinion, the most important among new advances in the amyloidosis problem. These proofs should become a basis for the study of disputable and unsolved problems in the pathogenesis of various types and forms of amyloidosis and development of its classification. The author suggests the schemes of the pathogenesis of AA- and AL-amyloidosis, indicated main and secondary features of a tentative amyloidosis classification.
作者认为,淀粉样纤维蛋白及其前体(血清和局部)的异质性证据是淀粉样变性问题新进展中最重要的。这些证据应成为研究各种类型和形式淀粉样变性发病机制中存在争议和未解决问题以及其分类发展的基础。作者提出了AA型和AL型淀粉样变性的发病机制方案,指出了暂定淀粉样变性分类的主要和次要特征。