Perry A M, Fox R A
Australas Phys Eng Sci Med. 1989 Dec;12(4):233-40.
Stereotactic radiosurgery is the accurate focusing of ionising radiation onto an intracranial target, and was pioneered in Sweden in the early 1950's. It has proven effective in the treatment of arteriovenous malformations, acoustic tumours and many other small brain lesions. In the last decade the commercial availability of a gamma ray system has led to other centres following the work in Stockholm; more recently, various techniques utilising linear accelerators, (LINACs), have been developed. Both types of system necessitated special dosimetry and treatment planning methods for the small, high dose-gradient circular fields. Localization of the lesions requires angiography, computerised tomography (CT) or magnetic resonance imaging (MRI).
立体定向放射外科是将电离辐射精确聚焦于颅内靶点,于20世纪50年代初在瑞典开创。它已被证明在治疗动静脉畸形、听神经瘤和许多其他小脑病变方面有效。在过去十年中,伽马射线系统的商业可用性促使其他中心效仿斯德哥尔摩的工作;最近,已经开发出了各种利用直线加速器(LINAC)的技术。这两种系统都需要针对小的、高剂量梯度圆形射野采用特殊的剂量测定和治疗计划方法。病变的定位需要血管造影、计算机断层扫描(CT)或磁共振成像(MRI)。