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疑似阑尾炎患者应省略口服对比剂吗?

Should Oral Contrast Be Omitted in Patients with Suspected Appendicitis?

作者信息

Saadat Lily, Helenowski Irene, Mahvi David, Boller Anne-Marie

机构信息

Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Department of Preventative Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

J Gastrointest Surg. 2016 Jun;20(6):1150-3. doi: 10.1007/s11605-016-3110-6. Epub 2016 Feb 29.

DOI:10.1007/s11605-016-3110-6
PMID:26925797
Abstract

BACKGROUND

Acute appendicitis is one of the most common surgical emergencies. Our study evaluated patients given the diagnosis of appendicitis and reviewed their workup and clinical outcomes. We specifically focused on the use of oral contrast followed by appendectomy.

METHODS

We retrospectively reviewed all adult patients given an ICD-9 code for appendicitis at Northwestern Memorial Hospital between January 2000 and September 2010. Complication rates, time to the operating room, and length of hospital stay were compared between patients who received a CT scan and those who did not during the hospitalization for appendicitis.

RESULTS

Average time from Emergency Department to the operating room was found to be statistically longer for patients who underwent a CT scan (10 h: 3, 1548) versus those who did not (6 h: 2, 262) (p < 0.0001). There were 19 patients who had the complication of pneumonia and 4 patients who were diagnosed with acute respiratory distress syndrome postoperatively. Patients who underwent a CT scan and received oral contrast had a statistically higher number of both complications (p < 0.0001).

CONCLUSIONS

The use of oral contrast is not necessary for an accurate diagnosis of appendicitis and may be associated with higher complication rates, longer hospital stays, and poor outcomes.

摘要

背景

急性阑尾炎是最常见的外科急症之一。我们的研究评估了被诊断为阑尾炎的患者,并回顾了他们的检查过程和临床结果。我们特别关注口服对比剂后行阑尾切除术的情况。

方法

我们回顾性分析了2000年1月至2010年9月在西北纪念医院被赋予国际疾病分类第九版(ICD-9)阑尾炎编码的所有成年患者。比较了阑尾炎住院期间接受CT扫描的患者和未接受CT扫描的患者的并发症发生率、进入手术室的时间和住院时间。

结果

发现接受CT扫描的患者从急诊科到手术室的平均时间在统计学上比未接受CT扫描的患者更长(10小时:3,1548例)对比(6小时:2,262例)(p<0.0001)。有19例患者发生肺炎并发症,4例患者术后被诊断为急性呼吸窘迫综合征。接受CT扫描并服用口服对比剂(造影剂)的患者这两种并发症的发生率在统计学上更高(p<0.0001)。

结论

口服对比剂对于准确诊断阑尾炎并非必要,且可能与更高的并发症发生率、更长的住院时间和不良预后相关。

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引用本文的文献

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本文引用的文献

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Enteral contrast in the computed tomography diagnosis of appendicitis: comparative effectiveness in a prospective surgical cohort.肠道造影剂在阑尾炎计算机断层扫描诊断中的应用:前瞻性手术队列中的比较效果
Ann Surg. 2014 Aug;260(2):311-6. doi: 10.1097/SLA.0000000000000272.
2
Emergency department experience with nonoral contrast computed tomography in the evaluation of patients for appendicitis.急诊部门在评估阑尾炎患者时使用非口服对比计算机断层扫描的经验。
J Patient Saf. 2014 Sep;10(3):154-8. doi: 10.1097/PTS.0b013e31829a07ba.
3
Examining the relevance of the physician's clinical assessment and the reliance on computed tomography in diagnosing acute appendicitis.
探讨医生临床评估与依赖计算机断层扫描诊断急性阑尾炎的相关性。
Am J Surg. 2013 Apr;205(4):452-6. doi: 10.1016/j.amjsurg.2012.07.038. Epub 2013 Feb 4.
4
Risk of perforation increases with delay in recognition and surgery for acute appendicitis.急性阑尾炎的穿孔风险随着对其认识和手术的延误而增加。
J Surg Res. 2013 Oct;184(2):723-9. doi: 10.1016/j.jss.2012.12.008. Epub 2012 Dec 27.
5
Do you need a computed tomographic scan to evaluate suspected appendicitis in young men: an administrative database review.是否需要 CT 扫描评估年轻男性疑似阑尾炎:行政数据库回顾。
Am J Surg. 2012 Dec;204(6):1025-30; discussion 1030. doi: 10.1016/j.amjsurg.2012.05.024. Epub 2012 Sep 28.
6
Intravenous contrast alone vs intravenous and oral contrast computed tomography for the diagnosis of appendicitis in adult ED patients.单纯静脉对比增强 CT 与静脉和口服对比增强 CT 用于诊断成人 ED 患者阑尾炎的比较。
Am J Emerg Med. 2012 Nov;30(9):1765-73. doi: 10.1016/j.ajem.2012.02.011. Epub 2012 May 23.
7
Low-dose abdominal CT for evaluating suspected appendicitis.低剂量腹部 CT 用于评估疑似阑尾炎。
N Engl J Med. 2012 Apr 26;366(17):1596-605. doi: 10.1056/NEJMoa1110734.
8
Changing epidemiology of acute appendicitis in the United States: study period 1993-2008.美国急性阑尾炎的流行病学变化:研究期间为 1993 年至 2008 年。
J Surg Res. 2012 Jun 15;175(2):185-90. doi: 10.1016/j.jss.2011.07.017. Epub 2011 Aug 9.
9
The lack of efficacy for oral contrast in the diagnosis of appendicitis by computed tomography.CT 诊断阑尾炎时口服对比剂无效。
J Surg Res. 2011 Sep;170(1):100-3. doi: 10.1016/j.jss.2011.02.017. Epub 2011 Mar 12.
10
Does enteral contrast increase the accuracy of appendicitis diagnosis?肠内造影剂能否提高阑尾炎诊断的准确性?
Radiol Technol. 2011 Mar-Apr;82(4):294-9.