Berg Evan R, Mehta Supriya D, Mitchell Patricia, Soto Jorge, Oyama Leslie, Ulrich Andrew
Department of Emergency Medicine, Boston University School of Medicine, Boston, MA, USA.
Acad Emerg Med. 2006 Oct;13(10):1040-5. doi: 10.1197/j.aem.2006.06.047. Epub 2006 Sep 13.
Studies show equivalent accuracy of abdominal computed tomography (CT) using rectal contrast compared with oral contrast for diagnosing appendicitis. The authors evaluated whether emergency department (ED) length of stay and satisfaction differed by route of contrast administration for abdominal CT.
This before-and-after intervention evaluated adult patients in an urban academic ED who were undergoing abdominal CT to screen for suspected appendicitis. Phase 1 subjects had a CT after oral contrast. Phase 2 patients had a CT after rectal contrast infused by gravity drip. Patients were interviewed after CT scan to assess satisfaction and discomfort. The primary outcome was ED length of stay. Medians, 95% binomial confidence intervals (CI), and Wilcoxon rank sum test of differences were calculated.
One hundred twelve patients were enrolled; half received rectal contrast. There was a significant decrease in length of stay for patients who were administered rectal contrast (261 min, 95% CI = 236 to 305 min) vs. oral contrast (332 min, 95% CI = 299 to 362 min), p = 0.009. Although subjects in the rectal-contrast group waited 65 minutes longer than did oral-contrast patients before receiving contrast after the CT order, the time from contrast administration to CT was 13 minutes, vs. 150 minutes for patients receiving oral contrast (p < 0.001). Patient satisfaction and discomfort did not differ by route of contrast administration.
Rectal contrast for patients undergoing abdominal CT to rule out appendicitis reduced ED length of stay by more than an hour and did not affect patient satisfaction or discomfort. Rectal-contrast administration for abdominal CT may significantly shorten patient throughput time for individuals undergoing evaluation for appendicitis.
研究表明,腹部计算机断层扫描(CT)使用直肠造影剂与口服造影剂在诊断阑尾炎方面具有同等准确性。作者评估了腹部CT造影剂给药途径对急诊科(ED)住院时间和满意度的影响。
这项前后对照干预研究评估了城市学术急诊科中接受腹部CT以筛查疑似阑尾炎的成年患者。第1阶段的受试者在口服造影剂后进行CT检查。第2阶段的患者在重力滴注直肠造影剂后进行CT检查。CT扫描后对患者进行访谈,以评估满意度和不适感。主要结局指标是ED住院时间。计算中位数、95%二项式置信区间(CI)以及差异的Wilcoxon秩和检验。
共纳入112例患者;其中一半接受直肠造影剂。接受直肠造影剂的患者住院时间(261分钟,95%CI = 236至305分钟)较接受口服造影剂的患者(332分钟,95%CI = 299至362分钟)显著缩短,p = 0.009。尽管直肠造影剂组的受试者在收到CT检查医嘱后等待造影剂的时间比口服造影剂组的患者长65分钟,但从给予造影剂到进行CT检查的时间为13分钟,而接受口服造影剂的患者为150分钟(p < 0.001)。患者满意度和不适感在造影剂给药途径方面没有差异。
对于接受腹部CT以排除阑尾炎的患者,直肠造影剂可使ED住院时间缩短超过1小时,且不影响患者满意度或不适感。腹部CT使用直肠造影剂给药可能会显著缩短阑尾炎评估患者的就诊时间。