Sofosbuvir and Simeprevir Treatment of a Stem Cell Transplanted Teenager With Chronic Hepatitis C Infection.
作者信息
Fischler Björn, Priftakis Peter, Sundin Mikael
机构信息
From the *Division of Pediatrics, CLINTEC, Karolinska Institutet; and †Department of Pediatrics, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
出版信息
Pediatr Infect Dis J. 2016 Jun;35(6):708-10. doi: 10.1097/INF.0000000000001122.
PMID:26928522
Abstract
There have been no previous reports on the use of interferon-free combinations in pediatric patients with chronic hepatitis C infection. An infected adolescent with severe sickle cell disease underwent stem cell transplantation and subsequent treatment with sofosbuvir and simeprevir during ongoing immunosuppression. Despite the emergence of peripheral edema as a side effect, treatment was continued with sustained antiviral response.
摘要
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