眼眶炎性假瘤的颅内蔓延：一例报告及文献复习
Intracranial extension of orbital inflammatory pseudotumor: a case report and literature review.
作者信息
Tedeschi Enrico, Ugga Lorenzo, Caranci Ferdinando, Califano Francesca, Cocozza Sirio, Lus Giacomo, Brunetti Arturo
机构信息
Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy.
Department of Clinical and Experimental Internal Medicine "F. Magrassi and A. Lanzara", Second University of Naples, Naples, Italy.
出版信息
BMC Neurol. 2016 Feb 29;16:29. doi: 10.1186/s12883-016-0550-2.
BACKGROUND
Orbital inflammatory pseudotumor is a rare inflammatory condition of unknown cause that may extend intracranially, usually as a dural-based infiltrate. Here we report the first case of orbital pseudotumor presenting with intra-axial Magnetic Resonance Imaging (MRI) changes.
CASE PRESENTATION
A 57-year-old white female, with a 3-month history of headache and right palpebral edema, presented with marked right temporal lobe edema with ominous MRI appearance, and ipsilateral alterations of orbital and periorbital structures. Following steroid therapy, both intracranial and orbital involvement dramatically improved.
CONCLUSION
Orbital inflammatory pseudotumor with chronic inflammation may infrequently present with intracranial involvement, mimicking more aggressive diseases, even showing intra-axial enhancement after i.v. contrast administration in brain MRI. Awareness of this possibility may help neurologists to choose the appropriate therapeutic approach.
背景
眼眶炎性假瘤是一种病因不明的罕见炎症性疾病，可向颅内蔓延，通常表现为硬膜下浸润。在此我们报告首例眼眶假瘤出现轴内磁共振成像（MRI）改变的病例。
病例报告
一名57岁白人女性，有3个月头痛及右眼睑水肿病史，就诊时表现为右侧颞叶明显水肿，MRI表现不祥，同时眼眶及眶周结构有同侧改变。经类固醇治疗后，颅内及眼眶病变均显著改善。
结论
伴有慢性炎症的眼眶炎性假瘤可能很少出现颅内受累，酷似更具侵袭性的疾病，甚至在静脉注射造影剂后脑部MRI显示轴内强化。认识到这种可能性有助于神经科医生选择合适的治疗方法。
Zotero 插件