Jayaraman Srinivasan
Department of Prosthodontics, Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth University, Pillayarkuppam, Puducherry, India.
J Indian Prosthodont Soc. 2015 Jan-Mar;15(1):65-9. doi: 10.4103/0972-4052.157055.
Cochrane reviews are systematic reviews with meta analysis published by the Cochrane collaboration, in the Cochrane Database of Systematic Reviews (CDSR). These reviews provide the clinicians with the highest level of evidence as they use a highly structured and transparent systematic review model to address a specific research question. The management of partially absent dentition is routinely under taken by general dentist and Prosthodontist but clinical practice guidelines based on evidence to this common problem is yet to be summarized. This Cochrane systematic review aims to address the effect of different prosthesis for the treatment of partially absent dentition in the terms of, Long-term success, function, morbidity, and patient satisfaction. All randomized controlled trials were searched till March 18, 2011, based on the inclusion and exclusion criteria, 21 trials were included and 32 trials were excluded and, it was critically appraised using the Cochrane methodology for interventions. The summary of evidence from the study concludes that there is insufficient evidence to state the effectiveness of removable and fixed prosthesis in partially edentulous subjects in the following four outcomes. There were insufficient trials to perform a meta-analysis and sensitivity analysis. This evidence-based summary emphasizes and reinforces the need to reassess the quality of research currently pursued in our profession, to address the need to provide higher level of evidence for common conditions like partial edentulousness. The included studies are basically not from our population too, hence the urgency to address this critical issue.
Cochrane综述是由Cochrane协作网在《Cochrane系统评价数据库》（CDSR）中发表的带有荟萃分析的系统评价。这些综述为临床医生提供了最高级别的证据，因为它们采用高度结构化且透明的系统评价模型来解决特定的研究问题。部分牙列缺损的治疗通常由普通牙医和口腔修复医生进行，但针对这一常见问题基于证据的临床实践指南尚未总结出来。这项Cochrane系统评价旨在从长期成功率、功能、发病率和患者满意度等方面探讨不同修复体治疗部分牙列缺损的效果。检索了截至2011年3月18日的所有随机对照试验，根据纳入和排除标准，纳入了21项试验，排除了32项试验，并使用Cochrane干预方法学对其进行了严格评价。该研究的证据总结得出结论，在以下四个结果方面，没有足够的证据表明可摘局部义齿和固定修复体在部分牙列缺损患者中的有效性。没有足够的试验进行荟萃分析和敏感性分析。这一基于证据的总结强调并强化了重新评估我们专业目前所开展研究质量的必要性，以满足为部分牙列缺损等常见情况提供更高水平证据的需求。纳入的研究基本上也不是来自我们的人群，因此迫切需要解决这一关键问题。
