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[转移性子宫绒毛膜癌导致的颅内肿瘤性动脉瘤破裂]

[Rupture of neoplastic intracranial aneurysm caused by metastatic uterine choriocarcinoma].

作者信息

Steimle R, Jacquet G, Billerey C, Godard J

出版信息

Chirurgie. 1989;115(6):393-6; discussion 396-7.

PMID:2692994
Abstract

Authors report a case of 18 years old woman with intracranial neoplastic aneurysm. Its rupture occurred one month after delivery, and the diagnosis of metastatic aneurysm from choriocarcinoma was made by pathologist. The craniotomy has allowed to remove the hematoma and the aneurysm with good immediate follow-up. In spite of X-ray-therapy and chemotherapy, the patient died one year after the outset from choriocarcinoma dissemination, in a comatose state. The review of the literature shows that this form of aneurysm is very exceptional. It is resulting from the invasion of the arterial wall by metastatic cells, by a neighbouring metastatic tumor or by another type of brain-tumor. In some cases, the aneurysmal rupture was the first symptom, before any gynecologic manifestation of the choriocarcinoma. The prognosis has been bad in such cases in spite of a commonly good response after chemotherapy.

摘要

作者报告了一例18岁患有颅内肿瘤性动脉瘤的女性病例。其破裂发生在分娩后一个月,病理学家诊断为绒毛膜癌转移性动脉瘤。开颅手术成功清除了血肿和动脉瘤,术后即刻随访情况良好。尽管进行了放疗和化疗,患者在绒毛膜癌播散开始一年后,处于昏迷状态死亡。文献回顾显示,这种类型的动脉瘤非常罕见。它是由转移细胞、邻近的转移瘤或另一种类型的脑肿瘤侵犯动脉壁所致。在某些情况下,动脉瘤破裂是绒毛膜癌任何妇科表现出现之前的首发症状。尽管化疗后通常反应良好,但此类病例的预后仍然很差。

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