Pullar M, Blumbergs P C, Phillips G E, Carney P G
J Neurosurg. 1985 Oct;63(4):644-7. doi: 10.3171/jns.1985.63.4.0644.
This case of metastatic gestational choriocarcinoma presented as intracerebral hemorrhage from an atypical distal middle cerebral artery aneurysm. Operative evacuation of the intracerebral hematoma was undertaken and histopathological examination revealed choriocarcinoma invading the vessel wall. Neoplastic cerebral aneurysms are unusual, being reported in metastatic choriocarcinoma, cardiac myxoma, bronchogenic carcinoma, and undifferentiated carcinoma. Metastatic choriocarcinoma should be considered in the differential diagnosis of intracerebral hemorrhage in women of child-bearing age. Recent advances in treatment have resulted in a 75% cure rate for metastatic choriocarcinoma.
该例转移性妊娠滋养细胞肿瘤表现为非典型大脑中动脉远端动脉瘤破裂导致的脑出血。进行了脑内血肿的手术清除,组织病理学检查显示绒毛膜癌侵犯血管壁。肿瘤性脑动脉瘤较为罕见,在转移性绒毛膜癌、心脏黏液瘤、支气管源性癌和未分化癌中均有报道。育龄期女性发生脑出血时,鉴别诊断应考虑转移性绒毛膜癌。近年来治疗方法的进展使转移性绒毛膜癌的治愈率达到了75%。