迈向一种用于运动单位数量评估的新方法（MUNIX）的验证。
Toward the validation of a new method (MUNIX) for motor unit number assessment.
作者信息
Stein Franziska, Kobor Ines, Bogdahn Ulrich, Schulte-Mattler Wilhelm J
机构信息
Department of Neurology, University Hospital Regensburg, Regensburg, Germany.
Department of Neurology, University Hospital Regensburg, Regensburg, Germany.
出版信息
J Electromyogr Kinesiol. 2016 Apr;27:73-7. doi: 10.1016/j.jelekin.2016.02.001. Epub 2016 Feb 21.
INTRODUCTION
This prospectively designed study analyzed the correlation of a new, non-invasive neurophysiological method (Motor Unit Number Index - MUNIX) with two established Motor Unit Number Estimation (MUNE) methods.
METHODS
MUNIX and incremental stimulation MUNE (IS-MUNE) were done in the abductor digiti minimi muscle (ADM), while MUNIX and spike-triggered averaging MUNE (STA-MUNE) were tested in the trapezius muscle. Twenty healthy subjects and 17 patients with amyotrophic lateral sclerosis (ALS) were examined.
RESULTS
MUNIX and MUNE values correlated significantly (ADM: n=108; Spearman-Rho; r=0.88; p<0.01; trapezius muscle: n=49; Spearman-Rho; r=0.46; p<0.01).
DISCUSSION
MUNIX indeed reflects the number of motor units in a muscle, and may sensibly be recorded from the trapezius muscle. With MUNIX being both much more patient friendly and much more rapid to assess than MUNE, the results support the use of MUNIX when motor unit number assessment is desired.
引言
这项前瞻性设计的研究分析了一种新的非侵入性神经生理学方法（运动单位数量指数 - MUNIX）与两种既定的运动单位数量估计（MUNE）方法之间的相关性。
方法
在小指展肌（ADM）中进行MUNIX和递增刺激MUNE（IS-MUNE），而在斜方肌中测试MUNIX和触发棘波平均MUNE（STA-MUNE）。检查了20名健康受试者和17名肌萎缩侧索硬化症（ALS）患者。
结果
MUNIX和MUNE值显著相关（ADM：n = 108；Spearman-Rho；r = 0.88；p < 0.01；斜方肌：n = 49；Spearman-Rho；r = 0.46；p < 0.01）。
讨论
MUNIX确实反映了肌肉中运动单位的数量，并且可以合理地从斜方肌中记录。由于MUNIX比MUNE对患者更友好且评估更快，因此在需要评估运动单位数量时，这些结果支持使用MUNIX。
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