Lieberman Elliot D, Thambi Rakhi, Pytynia Kristen B
Corresponding author: Kristen Pytynia, MD, MD Anderson Regional Care Center, 19770 Kingsland Blvd., Unit 2050, Suite 100, Houston, TX 77094. Email:
Ear Nose Throat J. 2016 Feb;95(2):70-2.
Methylene blue has been safely used for the localization of parathyroid glands during parathyroidectomy, and only a few adverse effects have been documented. Methylene blue administration as a cause of pulse-oximetry-related skin injury is extremely rare. We describe 2 such cases in patients who developed a blister on the second digit at the pulse oximetry site after an uncomplicated excision of a parathyroid adenoma. In another case, a patient became bradycardic intraoperatively; she was successfully resuscitated, but she incurred a second-degree burn at the pulse oximetry site. In all 3 cases, the burns resolved with local wound care. We publish this report to alert surgeons and anesthesiologists to the risk of skin complications with the use of high-dose intraoperative methylene blue.
亚甲蓝已被安全地用于甲状旁腺切除术中甲状旁腺的定位，且仅有少数不良反应的记录。作为脉搏血氧饱和度仪相关皮肤损伤原因的亚甲蓝给药极为罕见。我们描述了2例这样的病例，患者在甲状旁腺腺瘤简单切除术后，在脉搏血氧饱和度仪监测部位的示指上出现水疱。在另一例病例中，一名患者术中出现心动过缓；她成功复苏，但在脉搏血氧饱和度仪监测部位发生了二度烧伤。在所有3例病例中，烧伤通过局部伤口护理得以痊愈。我们发表本报告以提醒外科医生和麻醉医生注意术中使用高剂量亚甲蓝时发生皮肤并发症的风险。
