Localization of the parathyroid glands by intraoperative methylene blue staining.

Exploration of the neck for primary hyperparathyroidism has increased in our institution, as evidenced by nine patients treated in the past one year, as compared with six in the previous three years. Our experience indicates that methylene blue staining has served as an important adjunct in the localization of abnormal parathyroid glands. No complications were noted intraoperatively or postoperatively as a result of its use. Operating time was measurably decreased. The results of this study support the routine use of methylene blue in both primary and secondary parathyroid exploration, and this is currently being done in our institution.