[Potentiation of antidepressive treatment by thyroid hormone therapy. Review of the literature].

The association of thyroid hormone and antidepressant has been proposed for about twenty years, mainly for refractory depression treatment. Review of ten trials made since 1969 does not bring positive arguments in favor of this association (most of these trials have poor or no methodology). It is necessary to undertake double-blind placebo controlled studies on refractory depressed inpatients, in order to ascertain the real usefulness of this association.