Targum S D, Greenberg R D, Harmon R L, Kessler K, Salerian A J, Fram D H
J Clin Psychiatry. 1984 Aug;45(8):345-6.
Seven of 21 refractory depressed patients responded within 7 days to combined thyroid hormone-antidepressant treatment. Five of the 7 responders revealed evidence of subclinical hypothyroidism, suggesting that this subpopulation of depressed patients may benefit most from adjunctive thyroid hormone.
21名难治性抑郁症患者中有7人在接受甲状腺激素与抗抑郁药联合治疗7天内有反应。7名有反应者中有5人显示亚临床甲状腺功能减退的迹象,这表明这类抑郁症患者亚群可能从辅助甲状腺激素治疗中获益最多。