奥洛他定-抗组胺药-瞳孔、角膜及结膜对局部给药的反应。
Otrivine-antistin-pupil, corneal and conjunctival responses to topical administration.
作者信息
Trew D R, Wright L A, Smith S E
机构信息
Division of Pharmacological Sciences and Toxicology, United Medical School, St. Thomas's Campus, London.
出版信息
Eye (Lond). 1989;3 ( Pt 3):294-7. doi: 10.1038/eye.1989.41.
PMID:2693136
Abstract
The ocular effects of Otrivine-Antistin eyedrops have been measured in a placebo controlled single-blind study in sixteen healthy volunteers. The drops produced mild sympathomimetic responses in the eye but had no effect on corneal sensitivity or on intraocular pressure. The evidence indicates that use of Otrivine-Antistin imposes no risk to the subject.
摘要
在一项针对16名健康志愿者的安慰剂对照单盲研究中，已对奥洛他定-抗组胺滴眼液的眼部效应进行了测量。该滴眼液在眼部产生了轻微的拟交感神经反应，但对角膜敏感性或眼压没有影响。证据表明，使用奥洛他定-抗组胺滴眼液对受试者没有风险。
相似文献
1
Otrivine-antistin-pupil, corneal and conjunctival responses to topical administration.奥洛他定-抗组胺药-瞳孔、角膜及结膜对局部给药的反应。
Eye (Lond). 1989;3 ( Pt 3):294-7. doi: 10.1038/eye.1989.41.
2
Effects of oral administration of diphenhydramine on pupil diameter, intraocular pressure, tear production, tear film quality, conjunctival goblet cell density, and corneal sensitivity of clinically normal adult dogs.口服苯海拉明对临床正常成年犬瞳孔直径、眼压、泪液分泌、泪膜质量、结膜杯状细胞密度和角膜敏感性的影响。
Am J Vet Res. 2012 Dec;73(12):1983-6. doi: 10.2460/ajvr.73.12.1983.
3
[Antazoline/tetryzoline eyedrops in comparison with levocabastine eyedrops in acute allergic conjunctivitis].[安他唑啉/四氢唑啉滴眼液与左卡巴斯汀滴眼液治疗急性过敏性结膜炎的比较]
Klin Monbl Augenheilkd. 1997 Feb;210(2):93-6. doi: 10.1055/s-2008-1035023.
4
Effects of mydriatics on intraocular pressure and pupil size in the normal feline eye.散瞳剂对正常猫眼压和瞳孔大小的影响。
Vet Ophthalmol. 2006 Jul-Aug;9(4):233-7. doi: 10.1111/j.1463-5224.2006.00474.x.
5
[Double-blind study with cyclosporin A eyedrops in healthy probands].[健康受试者使用环孢素A滴眼液的双盲研究]
Klin Monbl Augenheilkd. 1986 Jul;189(1):44-5. doi: 10.1055/s-2008-1050747.
6
Corneal opacities secondary to topical naphazoline and antazoline (Albalon-A).局部使用萘甲唑啉和安他唑啉（Albalon-A）继发的角膜混浊。
Am J Ophthalmol. 1987 Jan 15;103(1):110-1. doi: 10.1016/s0002-9394(14)74185-6.
7
Safety and tolerability of naproxen ophthalmic solution in comparison to placebo.萘普生滴眼液与安慰剂相比的安全性和耐受性。
Int J Clin Pharmacol Ther. 1999 Mar;37(3):133-40.
8
9
Evaluation of adverse reactions of aponidine hydrochloride ophthalmic solution.盐酸阿扑尼定滴眼液不良反应的评价
J Ocul Pharmacol Ther. 1995 Fall;11(3):267-78. doi: 10.1089/jop.1995.11.267.
10
[Does Catapresan reduce the intraocular pressure independently from blood pressure?].[可乐定是否能独立于血压降低眼压？]
Klin Monbl Augenheilkd. 1971 Nov;159(5):574-7.
引用本文的文献
1
The management of ocular allergy in community pharmacies in the United Kingdom.英国社区药店中眼部过敏的管理。
Int J Clin Pharm. 2013 Apr;35(2):190-4. doi: 10.1007/s11096-012-9742-z. Epub 2013 Jan 1.
Zotero 插件