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[用含酪酸梭菌的整肠生与肠道疾病的治疗。一项多中心回顾性研究]

[The treatment of intestinal diseases with Mutaflor. A multicenter retrospective study].

作者信息

Schütz E

出版信息

Fortschr Med. 1989 Sep 30;107(28):599-602.

PMID:2693288
Abstract

The preparation Mutaflor contains a defined strain of physiological E. coli bacteria. One hundred and sixty-seven physicians documented the treatment of 1,074 patients suffering from functional or chronic inflammatory bowel disease. For all indications the tolerance of Mutaflor was judged to be good to very good in over 90% of the cases. Adverse reactions which needed treatment or led to termination of the therapy, were reported in 1.5% of the cases. Initially occurring side effects, which did not need treatment and disappeared spontaneously, were observed in 2.8% of the cases. Interactions with additional or concomitant drugs did not occur. As a parameter for the evaluation of efficacy, the subjective assessment of the results by physicians and patients was used. In 84% of the patients with functional intestinal disorders and 78% of the patients with chronic inflammatory bowel disease results of treatment were judged to be good to very good.

摘要

穆塔弗洛制剂含有特定菌株的生理性大肠杆菌。167名医生记录了对1074名患有功能性或慢性炎症性肠病患者的治疗情况。对于所有适应症,在超过90%的病例中,穆塔弗洛的耐受性被判定为良好至非常好。在1.5%的病例中报告了需要治疗或导致治疗终止的不良反应。在2.8%的病例中观察到最初出现的、无需治疗且自行消失的副作用。未发生与其他药物或同时使用药物的相互作用。作为疗效评估参数,采用了医生和患者对结果的主观评估。在84%的功能性肠道疾病患者和78%的慢性炎症性肠病患者中,治疗结果被判定为良好至非常好。

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