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去看牙医后发生的坏死梭杆菌引起的肝脓肿。

Hepatic abscess caused by Fusobacterium necrophorum after a trip to the dentist.

作者信息

Bytyci Faton, Khromenko Elena

机构信息

SHH, Allentown, Pennsylvania, USA.

出版信息

BMJ Case Rep. 2016 Mar 1;2016:bcr2015210235. doi: 10.1136/bcr-2015-210235.

DOI:10.1136/bcr-2015-210235
PMID:26933183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4785411/
Abstract

A 57-year-old man with no significant medical history was admitted to the hospital, with high-grade fever and right upper quadrant pain. He was found, on abdominal ultrasound, to have a right lobe hepatic cystic lesion. MRI of the abdomen confirmed a hepatic abscess. Cultures obtained under CT guidance showed the abscess to be caused by Fusobacterium necrophorum. This is a rare bacterium that can cause potentially fatal liver abscesses. Following drainage and intravenous antibiotic treatment, the patient improved and was discharged on a 4-week antibiotic course. An abdominal CT, performed 6 weeks after discharge, showed total resolution of the abscess. The patient had, 2 weeks prior to the development of the liver abscess, undergone routine dental cleaning. Neither upper respiratory symptoms nor sore throat had been identified prior to the presentation.

摘要

一名57岁无重大病史的男性因高热和右上腹疼痛入院。腹部超声检查发现他右叶有一个肝囊性病变。腹部MRI证实为肝脓肿。CT引导下获取的培养物显示脓肿由坏死梭杆菌引起。这是一种罕见的细菌,可导致潜在致命的肝脓肿。经过引流和静脉抗生素治疗,患者病情好转并出院,接受为期4周的抗生素疗程。出院6周后进行的腹部CT显示脓肿完全消退。该患者在肝脓肿发生前2周接受了常规牙齿清洁。在出现症状之前未发现上呼吸道症状或咽痛。

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本文引用的文献

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Increased incidence of gastrointestinal cancers among patients with pyogenic liver abscess: a population-based cohort study.化脓性肝脓肿患者胃肠道癌症发病率增加:一项基于人群的队列研究。
Gastroenterology. 2014 Jan;146(1):129-37.e1. doi: 10.1053/j.gastro.2013.09.058. Epub 2013 Oct 3.
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Lemierre's syndrome due to Fusobacterium necrophorum.坏死梭杆菌引起的李-孟二氏综合征。
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A case of pyogenic liver abscess infected with Fusobacterium necrophorum depicted by microscopy and confirmed by tissue culture.一例由坏死梭杆菌感染引起的化脓性肝脓肿,通过显微镜检查显示并经组织培养确诊。
Intern Med. 2011;50(17):1815-9. doi: 10.2169/internalmedicine.50.5147. Epub 2011 Sep 1.
4
Liver abscess caused by periodontal bacterial infection with Fusobacterium necrophorum.由坏死梭杆菌引起的牙周细菌感染导致的肝脓肿。
Hepatol Res. 2011 Feb;41(2):194-6. doi: 10.1111/j.1872-034X.2010.00748.x.
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Expand the pharyngitis paradigm for adolescents and young adults.扩展青少年和青年咽炎的范例。
Ann Intern Med. 2009 Dec 1;151(11):812-5. doi: 10.7326/0003-4819-151-11-200912010-00011.
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Lemierre syndrome following oropharyngeal infection: a case series.口咽感染后发生的勒米尔综合征:病例系列
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Population-based study of the epidemiology of and the risk factors for pyogenic liver abscess.基于人群的化脓性肝脓肿流行病学及危险因素研究。
Clin Gastroenterol Hepatol. 2004 Nov;2(11):1032-8. doi: 10.1016/s1542-3565(04)00459-8.
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QJM. 2002 Dec;95(12):797-802. doi: 10.1093/qjmed/95.12.797.