Nozawa Yuichi, Joshita Satoru, Fukushima Mana, Sugiyama Yukiko, Ichikawa Yuki, Kimura Takefumi, Morita Susumu, Kamijo Atsushi, Umemura Takeji, Ichijo Tetsuya, Matsumoto Akihiro, Yoshizawa Kaname, Tanaka Eiji
Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, Japan.
Intern Med. 2011;50(17):1815-9. doi: 10.2169/internalmedicine.50.5147. Epub 2011 Sep 1.
A 40-year-old man was admitted with a continuous high grade fever accompanying a relatively large solitary liver abscess with septations. A puncture of the abscess revealed gram-negative rods that could be identified histologically as Fusobacterium necrophorum, which was later confirmed by tissue culture. The patient was switched to meropenem and penicillin, and cured of the infection. Fusobacterium necrophorum is a rare bacterium causing potentially fatal liver abscesses in humans. Clinicians should bear Fusobacterium necrophorum in mind when treating patients with an enlarged solitary liver abscess.
一名40岁男性因持续高热伴一个相对较大的有分隔的孤立性肝脓肿入院。脓肿穿刺显示革兰氏阴性杆菌,经组织学鉴定为坏死梭杆菌,后经组织培养证实。患者改用美罗培南和青霉素治疗,感染得以治愈。坏死梭杆菌是一种罕见的细菌,可导致人类潜在致命的肝脓肿。临床医生在治疗患有孤立性肝脓肿肿大的患者时应考虑到坏死梭杆菌。