Galtrey Clare M, Mula Marco, Cock Hannah R
Epilepsy Group, Atkinson Morley Regional Neuroscience Centre, St George's University Hospitals NHS Foundation Trust, London, UK.
Epilepsy Group, Atkinson Morley Regional Neuroscience Centre, St George's University Hospitals NHS Foundation Trust, London, UK Institute of Biomedical & Medical Education, St George's University of London, London, UK.
Pract Neurol. 2016 Aug;16(4):270-8. doi: 10.1136/practneurol-2015-001337. Epub 2016 Mar 1.
People with epilepsy report that stress is their most common trigger for seizures and some believe it caused their epilepsy in the first place. The extensive preclinical, epidemiological and clinical studies examining the link between stress and epilepsy have given confusing results; the clinical studies in particular are fraught with confounders. However stress is clearly bad for health, and we now have substantial preclinical evidence suggesting that chronic stress worsens epilepsy; in selected cases it may even be a causal factor for epilepsy. Healthcare professionals working with people with epilepsy should pay more attention to stress in clinical practice. This review includes some practical advice and guidance for stress screening and management.
癫痫患者表示，压力是他们癫痫发作最常见的诱因，有些人认为压力首先导致了他们患上癫痫。大量的临床前、流行病学和临床研究都在探究压力与癫痫之间的联系，但结果却令人困惑；尤其是临床研究充满了混杂因素。然而，压力显然对健康有害，现在我们有大量临床前证据表明，慢性压力会使癫痫恶化；在某些特定情况下，压力甚至可能是癫痫的一个致病因素。为癫痫患者提供治疗的医护人员在临床实践中应更加关注压力问题。本综述包含了一些关于压力筛查和管理的实用建议与指导。
